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Research on neurophysiological and behavioral measures of attentional and inhibitory processes in adult young with ADHD

Published online by Cambridge University Press:  13 August 2021

L.R. Carreiro ,
A.A. Osório ,
M.C. Teixeira ,
W. Machado-Pinheiro ,
J. Nascimento  and
A. Afonso Junior
L.R. Carreiro*
Affiliation:
Developmental Disorders Graduate Program, Mackenzie Presbyterian University, São Paulo, Brazil
A.A. Osório
Affiliation:
Developmental Disorders Graduate Program, Mackenzie Presbyterian University, São Paulo, Brazil
M.C. Teixeira
Affiliation:
Developmental Disorders Graduate Program, Mackenzie Presbyterian University, São Paulo, Brazil
W. Machado-Pinheiro
Affiliation:
Departamento De Ciências Da Natureza, Universidade Federal Fluminense, Rio das Ostras, Brazil
J. Nascimento
Affiliation:
Developmental Disorders Graduate Program, Mackenzie Presbyterian University, São Paulo, Brazil
A. Afonso Junior
Affiliation:
Developmental Disorders Graduate Program, Mackenzie Presbyterian University, São Paulo, Brazil
*
*Corresponding author.

Abstract

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Introduction

Attention Deficit Hyperactivity Disorder (ADHD) is characterized by harmful levels of inattention, hyperactivity, and impulsivity and occurs in 2.5% of adults.

Objectives

This project will evaluate young adults with ADHD in computerized tasks that assess different forms of attention and inhibition, correlating them with self-report scales and physiological measurements (EMG and fNIRS) to identify impairments in specific cognitive domains.

Methods

The study will be conducted with two groups: one with ADHD - GClin and one control - CG, with 50 participants between 18 and 28 years each. Initially, participants will perform CPT-3 and respond to ASRS to be allocated to the CG or GClin, with validation by a specialist physician. After that, they will do the computerized inhibition (Stroop / Stop) temporal and spatial attention (voluntary and automatic) tests. In this phase the data will be collected using electromyographic measurements and recording of brain activity in areas of the prefrontal and temporal cortices through fNIRS. After the tests they will complete the impulsivity scales (BIS-11 and UPPS). The analyzes will comprise: (1) ANOVA of the means of TRs and the accuracy of the computerized tests; (2) Correlation analysis of RT, accuracy and ASRS scores; and (3) The fNIRS analysis will use the oxyhemoglobin signal, which will be analyzed individually.

Results

As expected results there will be differences between CG or GClin in relation to impulsiveness, number of errors and brain activation.

Conclusions

The integration of physiological measurements, scales and tests will ensure integrated understanding of attentional and inhibitory processes impaired in ADHD.

Disclosure

No significant relationships.

Keywords

ADHDtemporal and spatial attentionfNIRSinhibition
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S740
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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