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PW01-216 - The Impulsivity Changes Associated To Alcohol And Cocaine Use

Published online by Cambridge University Press:  17 April 2020

M. Aragues
Affiliation:
Department of Psychiatry, Hospital 12 de Octubre, Madrid, Spain CIBERSAM, Hospital 12 de Octubre, Madrid, Spain
G. Rubio
Affiliation:
Department of Psychiatry, Hospital 12 de Octubre, Madrid, Spain CIBERSAM, Hospital 12 de Octubre, Madrid, Spain
I. Martínez-Gras
Affiliation:
Department of Psychiatry, Hospital 12 de Octubre, Madrid, Spain CIBERSAM, Hospital 12 de Octubre, Madrid, Spain
G. Ponce
Affiliation:
Department of Psychiatry, Hospital 12 de Octubre, Madrid, Spain CIBERSAM, Hospital 12 de Octubre, Madrid, Spain
R. Rodriguez-Jimenez
Affiliation:
Department of Psychiatry, Hospital 12 de Octubre, Madrid, Spain CIBERSAM, Hospital 12 de Octubre, Madrid, Spain
A. Bagney
Affiliation:
Department of Psychiatry, Hospital 12 de Octubre, Madrid, Spain CIBERSAM, Hospital 12 de Octubre, Madrid, Spain
M.A. Jimenez-Arriero
Affiliation:
Department of Psychiatry, Hospital 12 de Octubre, Madrid, Spain CIBERSAM, Hospital 12 de Octubre, Madrid, Spain
T. Palomo
Affiliation:
Department of Psychiatry, Hospital 12 de Octubre, Madrid, Spain CIBERSAM, Hospital 12 de Octubre, Madrid, Spain

Abstract

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Impulsivity is associated with different types of disorders, included substance used disorders. The purposed of this study is get to know if alcohol and cocaine affect in the same way to the impulsivity paradigms or if they strength each other or if there are specific bias associated to each one of the substances.

Material and methods

This is a 380 heavy drinker patient's sample recruited from twelve primary care centers. The patients were screened using The Alcohol Use Disorders Identification Test (AUDIT > 8). Neuropsicological tests done at the base line and after the 4 years of the study were the Continous Performance Test (CPT) and the Barrat Impulsivity scale. The alcohol and cocaine consume accumulated along the four years was also study.

Results

The two variables of the CPT (ommission and commission errors) had a significant correlation with the alcohol and cocaine use accumulated in these four years. The variable that was associated with a greater risk of making more commission and ommission errors was the cocaine risk consumption. The years of study were protective variable.

Conclusions

The most important conclusion of this study is that alcohol and cocaine use produces a modification in the conductual paradigm of impulsivity characterized by the inhibition difficulties measured by the CPT. Also, the cocaine use effects are added respect to the alcohol ones and finally that cocaine plus alcohol effects over the number of ommission and commission errors are more potent that the ones made only with alcohol.

Type
Substance related disorders
Copyright
Copyright © European Psychiatric Association 2009
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