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PW01-187 - Treatment Of Insight In Schizophrenia Patients

Published online by Cambridge University Press:  17 April 2020

P. Piolino
Affiliation:
CNRS UMR 8160FRE 2987, Laboratoire de Psychologie et Neurosciences Cognitives, Université Paris Descartes, Paris, France Inserm-EPHE-Université de Caen-Basse Normandie, Unité E0218, Laboratoire de Neuropsychologie, CHU Côte de Nacre, Caen, Paris, France
M. Lalova
Affiliation:
Doctorante, Laboratoire de Psychologie et Neurosciences Cognitives, Groupe de Recherche Mémoire et Apprentissage, Université Paris Descartes, Paris, France Espace Jeune Adulte - SPASM Société Parisienne d’Aide à la Santé Mentale, Paris, France Université Paris V, Service Hospitalo-Universitaire de Santé Mentale et Thérapeutique, Hôpital Sainte-Anne, Paris, France
F. Baylé
Affiliation:
Université Paris V, Service Hospitalo-Universitaire de Santé Mentale et Thérapeutique, Hôpital Sainte-Anne, Paris, France

Abstract

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Background

Schizophrenia is the psychiatric disorder in which the awareness of pathology is most frequently altered. This merits particular attention, because related to medication compliance and clinical outcome.

Objectives

To improve the level of insight in stabilized schizophrenia patients by means of two cognitive remediation techniques: Cognitive remediation program for patients with a schizophrenia spectrum disease - ReCoS and autobiographical memory program - RemAu.

Methods

The study is based on the results of neurocognitive and insight evaluations before and after treatment of two groups of ten patients with RemAu and twenty patients with ReCoS. The level of insight is evaluated using the SUMD and the PANSS scales. For cognitive capacity we test their concentration level (Trail Making Test, TMT, Stroop), executive functions (Wisconsin Card Sorting Test, WCST), memory (CVLT), autobiographical memory (TempAu) and their global cognitive capacity (WAIS III).

Results

The results have enabled us to highlight the beneficial effects of the RemAu autobiographical reminiscence program on these patients’ insight. Although the ReCoS program does not significantly improve the level of insight, it produces results which are most satisfying with regard to the cognitive profile of each patient.

Conclusions

The patients who have most benefited from the program are those who already had a reasonable cognitive capacity before the treatment. This allows us to conclude that we should deliver a treatment which is directed simultaneously at persistent cognitive disorders and autobiographical memory in order to obtain optimal effect on the level of insight in this pathology.

Type
Psychotic disorders / Schizophrenia
Copyright
Copyright © European Psychiatric Association 2009
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