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Psychiatric disorders in low birthweight young adults. Prevalence and association with assessments at 11 years

Published online by Cambridge University Press:  15 April 2020

I.B. Elgen*
Affiliation:
Department of Clinical Medicine, University of Bergen, Bergen, Norway Department of Child and Adolescent Psychiatry, Haukeland University Hospital, Norway Department of Pediatric, Haukeland University Hospital, Norway
F. Holsten
Affiliation:
Department of Clinical Medicine, University of Bergen, Bergen, Norway
M.D. Odberg
Affiliation:
Department of Clinical Medicine, University of Bergen, Bergen, Norway
*
*Corresponding author. Department of Clinical Medicine, University of Bergen, N-5021 Bergen, Norway. Tel.: +47 55 97 4518; fax: +47 55 97 5146. E-mail address:[email protected] (I.B. Elgen).
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Abstract

Objective

To compare mental health of 136 young adults without neurosensory handicaps born with low birthweight (LBW, birthweight less than 2000 g) with 132 adults with normal birthweight (NBW).

Method

A cohort of moderate LBW and NBW young adults were assessed with the Mini-International Neuropsychiatric Interview (MINI) at 19 years and the Children Assessment Schedule (CAS) at 11 years of age.

Results

At 19 years of age, 44 out of 136 (32%) LBW young adults were diagnosed with a psychiatric disorder compared to 10% NBW (OR: 2.8; 95% CI: 1.1, 4.5, P = 0.02). Among the LBW young adults, affective-, anxiety-, ADHD- and antisocial personality disorders were most common, and nine subjects (20%) had more than one diagnosis. Of 97 LBW subjects examined both at 11 and 19 years of age, 54 (56%) were mentally healthy though out adolescence. This was half as many as for controls (OR: 0.6; 95% CI: 0.3 to 0.9).

Conclusion

Moderate LBW was associated with an increased risk of psychiatric disorders in young adulthood. Only half of LBW young adults stayed healthy throughout adolescence.

Type
Original article
Copyright
Copyright © European Psychiatric Association

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