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Prevalence of Maternal Psychological Distress in pregnant women who receipt prenatal diagnosis of fetal Central Nervous System (CNS) anomalies

Published online by Cambridge University Press:  01 September 2022

C. Falamesca ,
S. Cappelletti ,
R. Vicario ,
P.G. Amante ,
C. Correale ,
F. Vigevano ,
L. Caforio  and
T. Grimaldi Capitello
C. Falamesca*
Affiliation:
Bambino Gesù Children Hospital, Clinical Psychology Unit, Neurological Sciences Department, Rome, Italy
S. Cappelletti
Affiliation:
Bambino Gesù Children Hospital, Clinical Psychology Unit, Neurological Sciences Department, Rome, Italy
R. Vicario
Affiliation:
Bambino Gesù Children Hospital, Fetal Medicine And Surgery Unit, Department Of Medical And Surgical Neonatology, Rome, Italy
P.G. Amante
Affiliation:
Bambino Gesù Children Hospital, Neurosurgery Unit, Neurological Sciences Department, Rome, Italy
C. Correale
Affiliation:
Bambino Gesù Children Hospital, Clinical Psychology Unit, Neurological Sciences Department, Rome, Italy
F. Vigevano
Affiliation:
Bambino Gesù Children Hospital, Neurological Sciences Department, Rome, Italy
L. Caforio
Affiliation:
Bambino Gesù Children Hospital, Fetal Medicine And Surgery Unit, Department Of Medical And Surgical Neonatology, Rome, Italy
T. Grimaldi Capitello
Affiliation:
Bambino Gesù Children Hospital, Clinical Psychology Unit, Neurological Sciences Department, Rome, Italy
*
*Corresponding author.

Abstract

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Introduction

Women receiving a prenatal diagnosis of fetal anomalies are a high-risk population for psychological distress leading to mood disorders. Even so, to date we have no evidence of studies who investigated the levels of maternal anxiety and depression in pregnant women receiving a prenatal diagnosis of fetal CNS anomalies.

Objectives

The aim of this study was to assess the prevalence of anxiety and depression levels in a pilot sample of pregnant women at the Prenatal Diagnostic Unit of the Bambino Gesù Children Hospital.

Methods

We collected data among 43 women who receipt fetal brain anomaly diagnosis (mean age: 35 yrs, SD ± 6.3, range 19-48 yrs; mean week at first access 26w, SD ± 3.9, range 18-33w). Prenatal diagnosis including: ventriculomegaly (37.2%), posterior cranial fossa (23.3%), choroid plexus cysts (11.6%), anomalies of CC (7%) and other (20.9%). Pregnancies with assisted reproductive technology were 14%. We use the Patient Health Questionnaire (PHQ-9) and the Generalized Anxiety Disorders (GAD-7) questionnaires to assess anxious-depressive symptoms.

Results

showed a rate of mild-to-severe anxious depressive symptoms by 60.5% and 48.8% respectively. In detail: 41.9% mild, 14% moderate and 4.7% of severe anxiety. Meanwhile, 41.9% mild and 7% moderate depression. The prevalence of comorbid depressive and anxiety symptoms was 39.5% among the entire sample.

Conclusions

Preliminary data showed a high prevalence of anxious depressive symptoms and comorbidity among pregnant with CNS fetal anomalies. Women receiving a fetal CNS anomaly diagnosis may need additional psychological support or counselling.

Disclosure

No significant relationships.

Keywords

Prenatal diagnosisCNS anomaliesAnxietyDepression
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S616 - S617
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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