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P-777 - Body Mass Index and s100b Serum Protein Levels are not Related in Healthy Adult Subjects

Published online by Cambridge University Press:  15 April 2020

A.L. Morera-Fumero ,
P. Abreu-Gonzalez ,
M. Henry-Benitez ,
E. Diaz-Mesa ,
S. Yelmo-Cruz  and
R. Gracia-Marco
A.L. Morera-Fumero
Affiliation:
Department of Internal Medicine, Dermatology and Psychiatry, School of Medicine, University of La Laguna, Santa Cruz de Tenerife, Spain
P. Abreu-Gonzalez
Affiliation:
Department of Physiology, University of La Laguna, Spain
M. Henry-Benitez
Affiliation:
University Hospital of the Canary Islands, La Laguna, Spain
E. Diaz-Mesa
Affiliation:
University Hospital of the Canary Islands, La Laguna, Spain
S. Yelmo-Cruz
Affiliation:
University Hospital of the Canary Islands, La Laguna, Spain
R. Gracia-Marco
Affiliation:
University Hospital of the Canary Islands, La Laguna, Spain

Abstract

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Introduction:

S100B protein is an astroglial protein that can be measured in peripheral tissues such as blood, urine or saliva. S100B serum concentrations have been proposed as a maker of brain dysfunction. Body Mass Index (BMI) has been reported as a confounding variable in S100B measures.

Material and methods:

44 healthy subjects (24 female and 20 male, age 39.7 ± 9.4) participated in the study. Blood was sampled in July at 09:00, 12:00 and 24:00 h. Blood was centrifuged and serum was aliquot in Eppendorf tubes and frozen at −70° C. Serum S100B was measured by ELISA. S100B serum data are reported as pg/ml.

Results:

There were no significant correlations between BMI and any of the three S100B measures (09:00 h. r = 0.150, p = 0.339, 12:00 h. r=0.041, p = 0.794, 24:00 h. r=0.192, p = 0.223).

Conclusions:

Our results point to the fact that there are no relationships between BMI and S100B serum concentrations in healthy adult subjects.

Type
Abstract
Information
European Psychiatry , Volume 27 , Issue S1: Abstracts of the 20th European Congress of Psychiatry , 2012 , pp. 1
Copyright
Copyright © European Psychiatric Association 2012
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