Comparison of anxiety and depressive disorders (ADD) among persons with chronic CHD.

Patients (n = 301) with chronic CHD were: men 73% and women 27%. Age of women was 64,1 ± 9.9 years; men: 57.5 ± 9.9 years (p = 0,0000001). We used HADS, social adaptation and self-evaluation scales, and lipid range of blood. When anxiety and depression were more than 8 (HADS), diagnosis was verified by a psychiatrist (ICD-10).

In patients with CHD, anxiety (HADS) was 49.6%, and depression - 41.6%. Intensity of ADD among women was higher, than among men: anxiety level (HADS) was 9.3 ± 4.1 and 6.9 ± 3.6 respectively (p = 0,00005) and depression - 8.4 ± 3.4 and 6.6 ± 3.2 (p = 0,00009). Average score (social adaptation) was 34.9 ± 7.2. Frequency of ADD among inpatients with CHD was 42.6% (n = 130). Psychiatric diagnosis was: adaptation disorders 36.9% (n = 48), depressive episode 20% (n = 26), recursive depression 2.3% (n = 3), bipolar disorder 1% (n = 2), dysthymia 28.5% (n = 37), organic anxiety disorder 4.6% (n = 6), organic mood disorder 6.2% (n = 8). Women displayed more ADD than men: 40% (n = 32) vs. 22% (n = 49) (p = 0,05). Atypical depression was more often. Melancholic depression was less characteristic. Women displayed a higher total cholesterol than men: 6.4 ± 1.28 mmol/l and 5.4 ± 1.3 mmol/l respectively (p = 0,0000013) and low-density lipoprotein: 4.4 ± 1.11 mmol/l and 3.4 ± 1.1 mmol/l (p = 0,0007, respectively). 42.6% (n=130) of patients received medical correction of ADD. 97% of patients with chronic CHD on antidepressants, had stable rates of cardiovascular system.

We need integrated inter-institutional rehabilitation programs for patients with cardiovascular diseases and anxiety and depressive disorders taking into account their gender features.