Creatin phosphokinaze enzymes showed high levels when happened infarctus myocardii,rhabdomyolises, and neurolept malignant syndome. NMS is life threatening neurological disorder often caused as adverse reaction of use neuroleptics. its usually presented with high body temperature over 38C,rigidity of muscles, confussion or altered consciousness,autonomic imbalance,cpk eleveted plasma levels and diaphoresis known as sweat shock. NMS can ger peak of intensitiy in as little as 3 days if not threated and can lead to death.

In our study we traced levels of cpk, crp, liver enzmes among 70 patients after admission in urgent psychiatry nad the same parametars after one month. Among all patients, the first group 10 persons dg as f20,during admission had gor one amp of haloperidol im plus one amp lorazapam im. CPk were 4500 to 5000, the second group dg as f25, 40 persons got the same therapy. cpk were 2600 to 3000, the third group dg f 18, heroin iv addicts tried ts with tablets but not neuroleptics and cpk were 5000 to 6000,crp 70, hepatitis b.c.many scars on their skin were noticed.

After one month on intensive treatment in the first group cpk levels falled to 450, in the second group cpk normalized, and in the third group cpk stayed extremly high as were at start.

We diddnt observed other symptoms of NMS, just cpk. so. the question are what exactly means high levels of cpk in psychiatry without using neuroleptics? these patients had been got therapy,as mentioned just one day, the first day of admission.

Concluson 10%sch are sensitive.