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P-488 - Socio-demographic and Clinical Risk Factors on the Non-recovery of the Major Depressive Disorder: a 52-week Follow-up Study

Published online by Cambridge University Press:  15 April 2020

M. Gulec ,
Y. Selvi ,
M. Boysan ,
A. Aydin ,
L. Besiroglu  and
M.Y. Agargun
M. Gulec
Affiliation:
Department of Psychiatry, Ataturk University, Faculty of Medicine, Erzurum, Turkey
Y. Selvi
Affiliation:
Department of Psychiatry, Yuzuncu Yil University, Faculty of Medicine, Turkey
M. Boysan
Affiliation:
Department of Psychology, Yuzuncu Yil University, Faculty of Arts and Science, Van, Turkey
A. Aydin
Affiliation:
Department of Psychiatry, Yuzuncu Yil University, Faculty of Medicine, Turkey
L. Besiroglu
Affiliation:
Department of Psychiatry, Yuzuncu Yil University, Faculty of Medicine, Turkey
M.Y. Agargun
Affiliation:
Department of Psychiatry, Medipol Hospital, Istanbul, Turkey

Abstract

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Introduction:

Unfortunately, many patients who remit fully or partially from an episode of major depression continue to have difficulty in achieving the recovery.

Objectives:

Our study assesses the effect of some probable risk factors on the non-recovery in a group of major depressive patients.

Methods:

Sixty patients, 18 to 65 years of age, with current major depressive disorder defined using DSM-IV-TR criteria were participated in the study. They began a 24-week course of open-label acute plus continuation phase treatment mainly with SSRIs, especially escitalopram. Maintenance treatment was not planned for not affecting the natural course. All participants were evaluated by CGI-S, BDI, HAMD-17, PSQI, and ISI at weeks 0, 4, 12, 24, and 52.

Results:

Logistic regression analysis was done to predict the effect of some probable risk factors that obtained from 1st evaluation (at week 0) on the non-recovery (at week 52) and current age, number of previous episodes, age of first depressive episode, and episode type (first-episode versus double or chronic or recurrent) were found to be statistically significant.

Conclusions:

Early recognition of the socio-demographic and clinical risk factors impairing the recovery process of the major depressive disorder may be important for developing an individualised treatment plan.

Type
Abstract
Information
European Psychiatry , Volume 27 , Issue S1: Abstracts of the 20th European Congress of Psychiatry , 2012 , pp. 1
Copyright
Copyright © European Psychiatric Association 2012
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