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P300 event-related brain potential and personality in depression

Published online by Cambridge University Press:  16 April 2020

M. Hansenne ,
W. Pitchot ,
E. Pinto ,
J Reggers ,
P. Papart  and
M. Ansseau
M. Hansenne*
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
W. Pitchot
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
E. Pinto
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
J Reggers
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
P. Papart
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
M. Ansseau
Affiliation:
Department of Psychiatry, Centre Hospitalier Universitaire du Sart Tilman (B-35), B-4000Liège, Belgium
*
*Correspondence and reprints
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Summary

P300 is an event-related brain potential (ERP) particularly interesting to the study of cognitive processes in normal subjects and in psychopathology. P300 has been applied in depression with controversial results. A major source for these controversial results could result from the diversity of depressed patients included in the different studies. Supporting this assumption, impulsivity, blunted affect, suicidal behavior and psychotic features significantly influence P300 amplitude. However, no data are available on the possible influences of the personality of depressed patients on P300. Since personality is related to P300 in normal subjects, the aim of the present study is to investigate the relationship between ERPs (P200, N200, and P300) and the Temperament and Character Inventory (TCI) in 54 depressed patients. The main results of the study concern the absence of major correlations between personality dimensions as assessed by the TCI and ERP parameters among depressed patients. Only weak partial positive correlations relate N200 latency with harm avoidance, and P300 amplitude (Pz) with the self-directedness dimension. N200 amplitude is also negatively correlated to persistence. However, the preliminary nature of the presented results with respect to the weak statistical significance should be underlined.

Keywords

N200P200P300depressionpersonalityTCI
Type
Original article
Information
European Psychiatry , Volume 15 , Issue 6 , September 2000 , pp. 370 - 377
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2000

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