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P-279 - Bowel Symptoms and Retrieval of Invading Organisms in the Stools of Autistic Patients

Published online by Cambridge University Press:  15 April 2020

H. Essawy*
Affiliation:
Neuropsychiatry, Ain Shams University, Cairo, Egypt

Abstract

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Background:

The gut brain theory and pathogenesis of autism has long been suggested. Thus we analyzed stools of autistic children for some of the expected intestinal pathogens.

Patients and methods:

Thirty children with autism were diagnosed using ICD 10 classification criteria and Childhood Autism Rating Scale and Gilliam Autism Rating Scale. Stool analysis for detection of antigens of Giardia Lambila, Entamebea Histolytica antigen, Helicobacter pylori antigen, Cryptosporidium, Rotavirus and Adenovirus was performed for all patients.

Results:

Antigen retrieval in stools of the autistic patients revealed 40.0% Giardia Lambila antigen, 26.7% EH antigen, 13.3% H Pylori antigen, Cryptosporodium antigen 3.33%, 10.0% Adenovirus antigen and 20.0% Rotavirus antigen.

Conclusion:

By trial of retrieval of various pathogens from the stools of autistic patients as a reflection of the inflammatory reaction in the gut, we were able to partially disclose evidence of a link between the autistic disorder and active intestinal inflammation further proving the gut brain theory in autism.

Type
Abstract
Copyright
Copyright © European Psychiatric Association 2012
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