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P-1026 - Metabolic Syndrome and Risk for Coronary Heart Disease in Elderly Inpatients With Serious Mental Illness

Published online by Cambridge University Press:  15 April 2020

P. Ntounas ,
C. Tsopelas ,
P. Chatzimanolis ,
M. Dimitraka ,
D. Pappas ,
E. Siouti ,
C. Touloumis ,
A. Douzenis  and
L. Lykouras
P. Ntounas
Affiliation:
Psychiatric Hospital of Attica, National and Kapodistrian University of Athens, ‘Attikon’ General Hospital, Athens, Greece
C. Tsopelas
Affiliation:
Psychiatric Hospital of Attica, National and Kapodistrian University of Athens, ‘Attikon’ General Hospital, Athens, Greece
P. Chatzimanolis
Affiliation:
Psychiatric Hospital of Attica, National and Kapodistrian University of Athens, ‘Attikon’ General Hospital, Athens, Greece
M. Dimitraka
Affiliation:
Psychiatric Hospital of Attica, National and Kapodistrian University of Athens, ‘Attikon’ General Hospital, Athens, Greece
D. Pappas
Affiliation:
Psychiatric Hospital of Attica, National and Kapodistrian University of Athens, ‘Attikon’ General Hospital, Athens, Greece
E. Siouti
Affiliation:
Psychiatric Hospital of Attica, National and Kapodistrian University of Athens, ‘Attikon’ General Hospital, Athens, Greece
C. Touloumis
Affiliation:
Psychiatric Hospital of Attica, National and Kapodistrian University of Athens, ‘Attikon’ General Hospital, Athens, Greece
A. Douzenis
Affiliation:
2nd Dept. of Psychiatry, National and Kapodistrian University of Athens, ‘Attikon’ General Hospital, Athens, Greece
L. Lykouras
Affiliation:
2nd Dept. of Psychiatry, National and Kapodistrian University of Athens, ‘Attikon’ General Hospital, Athens, Greece

Abstract

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Introduction

People with severe mental disorders have worse physical health compared with the general population. Metabolic aspects such as obesity, diabetes, hypertension, dyslipidaemia, smoking and antipsychotic medication increase the risk of metabolic syndrome (MetS) and cardiovascular disease. Epidemiological studies have consistently shown excess CVD mortality in patients with schizophrenia, bipolar disorder and depression.

Methods

The participants (103 patients) age 55 years or more, had diagnosis of Schizophrenia and other psychotic disorders, Mood disorders and Mental disorders due to a general medical condition(DSM IV-TR criteria). Metabolic syndrome was estimated using the ATP III definition.

Framingham risk score was calculated using algorithms developed by Wilson for subjects aged 30 years and older.

Results

Overall prevalence of MetS was 34%. (37.1% men, 62,9% women). Among patients with MetS 74.3% had schizophrenia, 8.6.% Mood disorder and 17.1% Mental disorders due to a general medical condition. In our sample 18.8% of patients with MetS were receiving FGAs, 78.1% SGAs and 3.1% combination of FGAs and SGAs but this difference wasn’t statistically significant.

Low risk (FRS < = 14) had 68% of participants (21.4% men and 78.6% women). Moderate risk (FRS > 15) had 32% of participants (66.7% men, 33.3% women).

Conclusions

The results indicate that patients with schizophrenia have higher probability of having MetS, therefore, clinicians should appropriately monitor the risk factors and intervene as required.

Type
Abstract
Information
European Psychiatry , Volume 27 , Issue S1: Abstracts of the 20th European Congress of Psychiatry , 2012 , pp. 1
Copyright
Copyright © European Psychiatric Association 2012
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