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P0370 - Increase of prefrontal cortex blood flow during the performance of the computer version trail making test – the first report

Published online by Cambridge University Press:  16 April 2020

M. Kubo ,
C. Shoshi ,
T. Kitawaki ,
R. Takemoto ,
K. Kinugasa ,
H. Yoshida ,
C. Honda  and
M. Okamoto
M. Kubo
Affiliation:
Okayama University School of Health Sciences, Okayama, Japan
C. Shoshi
Affiliation:
Okayama University School of Health Sciences, Okayama, Japan
T. Kitawaki
Affiliation:
Okayama University School of Health Sciences, Okayama, Japan
R. Takemoto
Affiliation:
Okayama University School of Health Sciences, Okayama, Japan
K. Kinugasa
Affiliation:
Okayama Ryogo Center, Okayama, Japan
H. Yoshida
Affiliation:
Okayama Ryogo Center, Okayama, Japan
C. Honda
Affiliation:
Okayama Ryogo Center, Okayama, Japan
M. Okamoto
Affiliation:
Okayama University School of Health Sciences, Okayama, Japan

Abstract

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We measured concentration changes of oxyHb and deoxyHb in the prefrontal cortex during the performance of the computer version Trail Making Test(TMT) by multichannel NIRS using near infrared light pairs which are more sensitive for detecting changes of oxyHb and deoxyHb.

Sixteen healthy student volunteers performed four different TMT-A sets, and following 30 a sec resting period, two different TMT-B sets. Changes of oxyHb and deoxyHb were monitored by 22 channel NIRS from 30 sec before the start of TMT-A through 30 sec after the end of TMT-B. The mean changes in subjects over a period of 10 sec just before the start of TMT-A and TMT-B, and a period of 50 to 60 sec after the start of TMT-A and TMT-B were determined. OxyHb increased while deoxyHb decreased in the bilateral prefrontal cortices during the performance of TMT. The increase of oxyHb was prominent in the right lateral prefrontal cortex, especially during TMT-A.

On the other hand, deoxyHb significantly decreased in the bilateral prefrontal cortices especially during TMT-A.

The results suggest that blood flow increases in the prefrontal cortex during the performance of the computer version TMT.

Type
Poster Session I: Brain Imaging
Information
European Psychiatry , Volume 23 , Issue S2: 16th AEP Congress - Abstract book - 16th AEP Congress , April 2008 , pp. S190
Copyright
Copyright © European Psychiatric Association 2008
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