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P0335 - Effects of impairments in executive functions and semantics on speech disorganisation in schizophrenia

Published online by Cambridge University Press:  16 April 2020

M. Fadgyas Stanculete ,
I. Miclutia  and
R. Macrea
M. Fadgyas Stanculete
Affiliation:
University of Medicine and Pharmacy Iuliu Hatieganu Cluj Napoca, Department of Psychiatry, Cluj Napoca, Romania
I. Miclutia
Affiliation:
University of Medicine and Pharmacy Iuliu Hatieganu Cluj Napoca, Department of Psychiatry, Cluj Napoca, Romania
R. Macrea
Affiliation:
University of Medicine and Pharmacy Iuliu Hatieganu Cluj Napoca, Department of Psychiatry, Cluj Napoca, Romania

Abstract

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Background and Aims:

Semantic knowledge (long-established knowledge about objects, facts, and word meanings) is known to be impaired in schizophrenia. It has been hypothesized that language disorder in schizophrenia is linked both to executive and semantic dysfunctions.

Methods:

To examine this hypothesis we assessed 32 patients with schizophrenia (with and without formal thought disorder) and 30 matched normal controls. We compared the performances obtained by the two groups on the tests that evaluate executive functions (WCST) and semantic knowledge (Pyramids and Palm Tree Test). Test of verbal fluency were also applied.

Results:

Patients generally performed at a lower level than controls. Patient with thought disorder performed at a lower level on tests sensitive to executive dysfunction and semantic impairments.

Conclusion:

The results provide support for a dysexecutive hypothesis of formal thought disorder in schizophrenia and semantic processing.

Type
Poster Session II: Memory And Cognitive Disorders
Information
European Psychiatry , Volume 23 , Issue S2: 16th AEP Congress - Abstract book - 16th AEP Congress , April 2008 , pp. S291
Copyright
Copyright © European Psychiatric Association 2008
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