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P03-254 - Antidepressants In Treatment Of Opiate Post-Detoxication Depressive Syndrome

Published online by Cambridge University Press:  17 April 2020

A. Ramah  and
M. Todorovic
A. Ramah
Affiliation:
Private Practice ‘Ramah’, Belgrade, Serbia
M. Todorovic
Affiliation:
Institute for Mental Health, Belgrade, Serbia

Abstract

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Withdrawal syndrome and post-detoxication period in opiate addicts is characterized by different psychopathologic phenomena including the depressive syndrome.

The aim was to determine the response of the depressive symptoms in opiate post-detoxication syndrome to antidepressants.

Within the sample of 54 heroin addicts detoxified in the period June 2008 to December 2008, 33% were diagnosed as depression requiring treatment with antidepressants.

The assessment of depression performed 21 day after the last use of opiate by means of CGI-S scale and the improvement during the treatment by CGI-I scale. Duration of the treatment lasted 4 months on average.

The results show reduction in depressive symptoms registered in 83% of patients for at least one point on the CGI-I scale, also patients were kept in the treatment programme approximately 2 mounths longer than average.

Opiate post-detoxication syndrome with depressive symptoms indicates antidepressant use and resulted in remission or recovery of symptoms and improves possibilities to keep patients in integrative treatment program

Type
Substance related disorders
Information
European Psychiatry , Volume 25 , Issue S1: 18th European Congress of Psychiatry. February 27, March 2, 2010 - Munich, Germany , 2010 , 25-E1308
Copyright
Copyright © European Psychiatric Association 2010

References

Edward, V. Nunes, MD; Frances, R. Levin, MD, Treatment of Depression in Patients With Alcohol or Other Drug Dependence, JAMA. 2004;291:1887-1896.Google Scholar
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Le Fauve Review antidepressants are moderately effective in people with depression and a substance dependence disorder, Evid. Based Ment. Health 2004;7:108-108.CrossRefGoogle Scholar
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