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P0311 - Interest of TMS treatment in resistant depressed patient with Parkinson's disease: A case report

Published online by Cambridge University Press:  16 April 2020

R. Benadhira
Affiliation:
Unite de Recherche Clinique, Service Psychiatrie 93G03, EPS Ville Evrard, Saint Denis, France
S. Braha
Affiliation:
Unite de Recherche Clinique, Service Psychiatrie 93G03, EPS Ville Evrard, Saint Denis, France
D. Sidhoumi
Affiliation:
Unite de Recherche Clinique, Service Psychiatrie 93G03, EPS Ville Evrard, Saint Denis, France
D. Januel
Affiliation:
Unite de Recherche Clinique, Service Psychiatrie 93G03, EPS Ville Evrard, Saint Denis, France

Abstract

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Repetitive transcranial magnetic stimulation treatment (rTMS) in elderly depressed subjects (> 60 years) deserves to be assessed, in view of the absence of severe side effects. But most of the results in the literature have been negative probably due to a too short duration of rTMS treatment in this particular population.We report the case of a 71 years resistant depressed old man with a Parkinson's disease treated by rTMS (LDLPFC, 10 Hz, 1600 pulses, 80% MT) over a 2 years period: one month of curative treatment (five sessions a week) followed by 23 months of maintenance sessions (one a week). The results show a significant drop in HDRS scores after one month of rTMS: 26 at baseline versus 10 at M1, 7 at M6 maintained at M24. Therapeutic efficacy and absence of cognitive effects are strong arguments in favour of rTMS treatment in resistant depressed patient with parkinson's disease. Moreover, rTMS could be useful to avoid aggravating the polymedication in this multitreaded population. Double blind studies are needed to confirm the interest of rTMS in this population.

Type
Poster Session II: ECT/ TMS
Copyright
Copyright © European Psychiatric Association 2008
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