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P0226 - Acute and transient psychotic disorders: Do ICD-10 criteria identify a distinct category?

Published online by Cambridge University Press:  16 April 2020

S.P. Singh
S.P. Singh*
Affiliation:
Health Sciences Research Institute, University of Warwick, Coventry, UK

Abstract

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Background and Aims:

The Kraepelinian division of endogenous psychoses does not satisfactorily account for Acute and transient psychotic disorders (ATPD), which have been reported world-wide.

Methods:

All patients with first-episode psychosis identified in Nottingham between 1992-1994 and diagnosed using ICD10 criteria were reassessed three years later. ATPD outcomes were compared with schizophrenia and affective psychosis. Multivariate analyses were conducted to determine whether acute onset and early remission predicted favourable outcome in first episode psychosis.

Results:

Of 168 cases of first-episode psychosis, 32 (19%) received an intake diagnosis of ATPD. At three years ATPD diagnosis was stable only in women. ATPD outcomes were better than schizophrenia and similar to affective psychosis. Overall, in non-affective psychoses, favourable outcomes were a function of gender and good premorbid functioning rather than acute onset and early remission.

Conclusions:

ICD-10 ATPD criteria identify a diagnostically unstable group of disorders. Acute onset and early remission per se do not independently predict favourable outcome in first episode psychosis. Alternative definitions and criteria for ATPD, including operational criteria for acute onset will be discussed.

Type
Poster Session I: Schizophrenia and Psychosis
Information
European Psychiatry , Volume 23 , Issue S2: 16th AEP Congress - Abstract book - 16th AEP Congress , April 2008 , pp. S147
Copyright
Copyright © European Psychiatric Association 2008

References

Singh, SP, Burns, T, Amin, Set al (2004) Acute and transient psychotic disorders: precursors, epidemiology, course and outcome. Br J Psychiatry. 85:452–9.10.1192/bjp.185.6.452CrossRefGoogle Scholar
Singh, SP, Cooper, J, Fisher, Het al (2005) Determining the chronology and components of psychosis onset: The Nottingham Onset Schedule (NOS). Schizophr Res. 80(1):117–30.10.1016/j.schres.2005.04.018CrossRefGoogle Scholar
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