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P0221 - What is the role of HIV positivity in patients with ESLD who undergo to OLTx Iter?

Published online by Cambridge University Press:  16 April 2020

V. Barbanti Silva ,
M. Ferrara ,
L. Pingani ,
F. Mazzi ,
S. Cocchi ,
G. Guaraldi ,
A. Romano ,
M. Masetti ,
G.E. Gerunda  and
M. Rigatelli
V. Barbanti Silva
Affiliation:
Department of Neuroscience, TCR – University of Modena and Reggio Emilia, Modena, Italy
M. Ferrara
Affiliation:
Department of Neuroscience, TCR – University of Modena and Reggio Emilia, Modena, Italy
L. Pingani
Affiliation:
Department of Neuroscience, TCR – University of Modena and Reggio Emilia, Modena, Italy
F. Mazzi
Affiliation:
Department of Neuroscience, TCR – University of Modena and Reggio Emilia, Modena, Italy
S. Cocchi
Affiliation:
Department of Infectivology – University of Modena and Reggio Emilia, Modena, Italy
G. Guaraldi
Affiliation:
Department of Infectivology – University of Modena and Reggio Emilia, Modena, Italy
A. Romano
Affiliation:
Department of General and Transplantation Surgery – University of Modena and Reggio Emilia, Modena, Italy
M. Masetti
Affiliation:
Department of General and Transplantation Surgery – University of Modena and Reggio Emilia, Modena, Italy
G.E. Gerunda
Affiliation:
Department of General and Transplantation Surgery – University of Modena and Reggio Emilia, Modena, Italy
M. Rigatelli
Affiliation:
Department of Neuroscience, TCR – University of Modena and Reggio Emilia, Modena, Italy

Abstract

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Introduction:

Since 2003 the national research program for solid organ transplantation in HIV patients is active at the Liver Transplantation Centre of Modena. HIV patients who enter this protocol are assessed by the CLP Service. The aim of the present study is to evaluate their psychiatric comorbidity.

Methods:

An observational prospective study was conduced comparing ESLD patients with and without HIV. After the assessment, the psychiatrist compiled the TERS and the MADRS. Baseline (B) evaluation was made before the inclusion in the OLTx waiting list and the Follow-Up (FU) one was made 12 months later.

Results:

From January 2003 to December 2006 we assessed 553 patients: 39 (6%) with HIV and 361 (94%) without HIV. The two groups were homogeneous for gender (75% of male patients; p = ns) but not for age (46 ± 5 vs 56 ± 9; p = ns). Psychiatric anamnesis was negative in 176 (49%) patients without HIV and in 6 (15%) patients with HIV, p<0.001.

At baseline psychiatric comorbidity was present in 33 HIV patients (85%) and in 148 non HIV patients (41%), p<0.001.

At the follow-up MADRS highlights an improvement at all the items for HIV patients. In the non-HIV group score variation was: B = 7.10, FU = 8.15; in the HIV group: B = 10.20, FU = 4.09 (p<0.001).

The average score at TERS was higher in patients with HIV (43 ± 9 vs 35 ± 9, p = ns).

Conslusions:

At B HIV patients with ESLD show a greater frailty to psychopathology but they quite improved during FU. The contrary happen in non-HIV group.

Type
Poster Session III: Miscellaneous
Information
European Psychiatry , Volume 23 , Issue S2: 16th AEP Congress - Abstract book - 16th AEP Congress , April 2008 , pp. S365 - S366
Copyright
Copyright © European Psychiatric Association 2008
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