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P0175 - Identifying schizophrenic psychoses with psychological scales - the northern Finland 1966 birth cohort

Published online by Cambridge University Press:  16 April 2020

J. Miettunen ,
J. Veijola ,
M.K. Isohanni ,
T. Paunio ,
N. Freimer ,
E. Jaaskelainen ,
J. Ekelund ,
L. Peltonen ,
M. Joukamaa  and
D. Lichtermann
J. Miettunen
Affiliation:
Department of Psychiatry, Oulu University and Oulu University Hospital, Oulu, Finland
J. Veijola
Affiliation:
Department of Psychiatry, Oulu University and Oulu University Hospital, Oulu, Finland Academy of Finland, Helsinki, Finland
M.K. Isohanni
Affiliation:
Department of Psychiatry, Oulu University and Oulu University Hospital, Oulu, Finland Department of Public Health and General Practice, University of Oulu, Oulu, Finland
T. Paunio
Affiliation:
Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland
N. Freimer
Affiliation:
Center for Neurobehavioral Genetics, Semen Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA
E. Jaaskelainen
Affiliation:
Department of Psychiatry, Oulu University and Oulu University Hospital, Oulu, Finland
J. Ekelund
Affiliation:
Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
L. Peltonen
Affiliation:
Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland
M. Joukamaa
Affiliation:
Social Psychiatry Unit, Tampere School of Public Health, University of Tampere, Tampere, Finland Department of Psychiatry, Tampere University Hospital, Tampere, Finland
D. Lichtermann
Affiliation:
Methadone Maintenance Clinic “Café Ersatz”, Bonn, Germany

Abstract

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Background and Aims:

We study the predictive power and associations of several psychological scales with respect to hospitalisations due to schizophrenic psychoses.

Methods:

Temperament and Character Inventory, Physical Anhedonia Scale, Social Anhedonia Scale, Perceptual Aberration Scale, Hypomanic Personality Scale, Bipolar II Scale, and Schizoidia Scale were included in the 31-year follow-up survey of the prospective Northern Finland 1966 Birth Cohort (N=4,926). We compared subjects without any previous hospitalisations to those with previous hospital diagnoses (concurrent validity) and to those who in the eight year long follow-up were hospitalised due to schizophrenic psychosis (predictive validity). We also compared the subjects with schizophrenic psychoses and subjects with other psychiatric disorders (discriminant validity).

Results:

In most scales, subjects with schizophrenic psychoses differed from healthy subjects. The Perceptual Aberration Scale was the best scales for concurrent (Effect Size, d = 1.89) and discriminant validity (d = 0.64). Subjects having a high score in Hypomanic Personality Scale were in the highest risk for schizophrenic psychoses (OR 10.72; 95% CI 2.87-40.06).

Conclusions:

Subjects with schizophrenic psychoses differed in most of the scales from healthy controls and from subjects with other psychiatric disorders. Many of the scales were useful predictors for future hospitalisations due to schizophrenic psychoses; however scales were not very diagnosis specific. The predictive power of the scales is limited, these scales are probably not useful as screening instruments but can be used in several ways when studying e.g. risk factors or genetics of schizophrenic psychoses.

Type
Poster Session I: Schizophrenia and Psychosis
Information
European Psychiatry , Volume 23 , Issue S2: 16th AEP Congress - Abstract book - 16th AEP Congress , April 2008 , pp. S132
Copyright
Copyright © European Psychiatric Association 2008
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