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P0165 - EEG abnormalities and three year outcome in first episode psychosis

Published online by Cambridge University Press:  16 April 2020

R. Manchanda ,
R. Norman ,
A. Malla ,
R. Harricharan  and
S. Northcott
R. Manchanda
Affiliation:
Departyment of Psychiatry, University of Western Ontario, London, ON, Canada
R. Norman
Affiliation:
Departyment of Psychiatry, University of Western Ontario, London, ON, Canada
A. Malla
Affiliation:
Department of Psychiatry, McGill University, Montreal, QU, Canada
R. Harricharan
Affiliation:
Departyment of Psychiatry, University of Western Ontario, London, ON, Canada
S. Northcott
Affiliation:
Departyment of Psychiatry, University of Western Ontario, London, ON, Canada

Abstract

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Objectives:

This study assesses the relationship of EEG to several aspects of 3 year symptomatic and functional outcome in first episode psychosis.

Method:

One hundred and seventeen patients with first episode psychosis had their baseline EEG classified by modified Mayo Clinic criteria as normal, essentially normal or dysrhythmia. Socio-demographic variables, duration of illness and of untreated psychosis and premorbid adjustment were also recorded. Positive and negative symptoms of psychoses, depression, anxiety and global functioning were rated on entry and after three years of treatment.

Results:

Patients with a dysrhythmic EEG at entry into treatment showed significantly greater persistence in both positive and negative symptoms of psychoses as well as anxiety and depression over three years. These findings were independent of duration of untreated illness or premorbid adjustment.

Conclusion:

An abnormal baseline EEG in patients with first episode psychosis is associated with a poorer symptomatic outcome at three year follow-up.

Keywords

first episode psychosisEEGoutcomeschizophreniaDUP
Type
Poster Session I: Schizophrenia and Psychosis
Information
European Psychiatry , Volume 23 , Issue S2: 16th AEP Congress - Abstract book - 16th AEP Congress , April 2008 , pp. S129
Copyright
Copyright © European Psychiatric Association 2008
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