For the period of 2002-2007 -102 male alcoholics aged 23-45 (mean age 31) were investigated. They had their first panic disorder during an alcoholic abstinence. Common for all patients was the following: duration of alcoholic dependence over 5 years, the use of strong alcoholic drinks (vodka, cognac), duration of the continuous use of alcohol up to the moment of development of panic disorder more than 3 days. Panic disorders arose on a background of various vegetative abnormalities in the abstinent period. In an ideatoric part of panic disorders there were mentioned the following conditions: a frank fear of dying or development of a heart attack or a stroke, feeling of anxiety. Therapeutic actions as the ordinary parenteral injections of Diazepam 10-20 mg, in a combination with Obzidanum 40 mg have given short-term effect till 4-5 hours. Frequency of repeated attacks reached 2-3 times within 3 days. The most effective solution was a realization of a detoxication in a combination with Diazepam up to 40 mg per day, with the subsequent purpose of sedative traditional neuroleptics within 3-4 days (in the present research Promazin in a doze of 75 mg per day was prescribed).

After the completion of an abstinence with panic disorders a part of patients (12 %) stopped reception of alcohol, 88 % of patients considerably reduced a doze of the use of alcohol for the period till 6 months. Renewal of reception of alcohol in former intoxicated conten resulted in the development of repeated panic disorders.