Case report of a 44 years old female patient, highly educated, suffering from Borderline personality disorder with co-occurring mood disorder, present episode depressive who suffered from acute emotional stress for a few months. She was in a process of divorce and losing her children by order of the court. In a two months period she has lost over a 90% of her hair and started treatment for alopecia areata. Dermatologist and psychiatrist treated her simultaneously; she also went on group psychotherapy. The influence of psychological factors in the development, evolution and therapeutic management of alopecia areata is documented in this case. Life events and intrapsychically generated stress played an important role in triggering of the disease. The role of treatment on concomitant psychopathological disorders is a vital one in this case because it positively affected how the patient adapted to her alopecia areata and social setting and led to a better dermatological evolution of the alopecia areata.