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Overlapping of clinical symptoms between schizophrenia and bipolar disorder

Published online by Cambridge University Press:  01 September 2022

A. Tahirovic ,
M. Arnautović Tahirović ,
M. Muhic ,
H. Sikira ,
G. Sulejmanpasic ,
L. Haracic Curovac ,
A. Cesir  and
A. Memic Serdarevic
A. Tahirovic*
Affiliation:
Clinical Centre University of Sarajevo, Psychiatric Clinic, Sarajevo, Bosnia and Herzegovina
M. Arnautović Tahirović
Affiliation:
Psychiatric Hospital of Canton Sarajevo, Clinical Psychiatry, Sarajevo, Bosnia and Herzegovina
M. Muhic
Affiliation:
Clinical Centre University of Sarajevo, Psychiatric Clinic, Sarajevo, Bosnia and Herzegovina
H. Sikira
Affiliation:
Clinical Centre University of Sarajevo, Psychiatric Clinic, Sarajevo, Bosnia and Herzegovina
G. Sulejmanpasic
Affiliation:
Clinical Centre University of Sarajevo, Psychiatric Clinic, Sarajevo, Bosnia and Herzegovina
L. Haracic Curovac
Affiliation:
Clinical Centre University of Sarajevo, Psychiatric Clinic, Sarajevo, Bosnia and Herzegovina
A. Cesir
Affiliation:
Clinical Centre University of Sarajevo, Psychiatric Clinic, Sarajevo, Bosnia and Herzegovina
A. Memic Serdarevic
Affiliation:
Clinical Centre University of Sarajevo, Psychiatric Clinic, Sarajevo, Bosnia and Herzegovina
*
*Corresponding author.

Abstract

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Introduction

Schizophrenia (SCH) and bipolar affective disorder (BP) are complex disorders that overlapping both in their clinical symptoms and certain familiar characteristics. They share some common characteristcs but there are also key differences. The frequency of overlapping symptoms between these diseases could give us more information about the current validity of the diagnosis based on existing diagnostic criteria. Similarities within and between these two disorders in the future, can possibly redefine greater reliability of diagnosis.

Objectives

The aim of the study was to investigate the frequency of overlapping symptoms between BP and SCH.

Methods

The sample included 159 patients diagnosed with SCH and 61 with BP who were followed over a two year period. The research was conducted at the UCCS Psychiatric Clinic. Assessment of clinical symptoms and diagnosis were performed using a structured clinical interview (SCID I), a list of operationalized criteria (OPSCRIT), a scale for the assessment of positive and negative symptoms (PANSS), a scale for the assessment of manic symptoms (YMRS).

Results

The overall PANSS score was significantly higher in patients with SCH compared to patients with BP, but on the general psychopatology there are no significant differences betwen SCH and BP. Symptoms of mania are significantly more pronounced in patients with BP compared to those with SCH.

Conclusions

Our results of overlapping of individual symptoms between SCH and BP can speak infavor of the theory of disease continuum. And can also help us in understanding symptoms and guide us to develop optimal treatment strategies.

Disclosure

No significant relationships.

Keywords

schizophréniaYMRSPANSSBipolar Affective Disorder
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S362
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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