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Overdose with sustained-release lithium preparations

Published online by Cambridge University Press:  16 April 2020

B Astruc ,
P Petit  and
M Abbar
B Astruc
Affiliation:
Department of Psychiatry, Caremeau Hospital, 30000Nîmes
P Petit
Affiliation:
Department of Psychopharmacology, La Colombière Hospital, 34000Montpellier, France
M Abbar
Affiliation:
Department of Psychiatry, Caremeau Hospital, 30000Nîmes
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Summary

Acute lithium intoxication is potentially lethal. Compared to conventional lithium preparations, sustained-release lithium formulations present specific problems for medical practice in the case of overdose. We report a case of intoxication with 8000 mg of sustained-release lithium carbonate preparation (Teralithe 400 LP®). Twenty-five hours after the ingestion, the patient was still asymptomatic, despite a serum level in the toxic range. After comparison of this case with reports found in the Medline database, we consider the clinical management of such cases.

Keywords

overdosesuicide attemptsustained-release lithium preparation
Type
Case Reports
Information
European Psychiatry , Volume 14 , Issue 3 , June 1999 , pp. 172 - 174
Copyright
Copyright © European Psychiatric Association 1999

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