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Outpatient treatment of acute psychotic episode with neuroleptic infusions: a retrospective study

Published online by Cambridge University Press:  16 April 2020

CL Bonsack
Affiliation:
Policlinique Psychiatrique Universiraire A, Service A, Département Universitaire de Psychiatric Adulte (DUPA), 18 av de Sévelin, 1004Lausanne, Swirzerland
R Philippoz
Affiliation:
Policlinique Psychiatrique Universiraire A, Service A, Département Universitaire de Psychiatric Adulte (DUPA), 18 av de Sévelin, 1004Lausanne, Swirzerland
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Summary

In this retrospective pragmatic study, we define the necessary conditions that allow outpatient low dose intravenous neuroleptization, when hospitalization should otherwise be required. Intravenous neuroleptization is infrequently used in the outpatient treatment of acute psychotic decompensation. Rapid tranquilization with high dosage neuroleptics is controversial, and has a high risk of side effects. The indications for and potential advantages of this method in the perspective of a long-term ambulatory treatment are discussed by comparing a group of outpatients treated with infusions to a group of hospitalized patients. The method offers a satisfactory alternative to hospitalization for subjects who are not in imminent danger (current GAF rating between 20 and 40) and whose normal functioning is good (past year GAF rating = 70). Previous repeated hospitalizations favor the choice of hospitalization over infusion. Its potential advantages are the rapid evolution of the condition, with controlled regression but without psychosocial withdrawal, and an improvement in the patient's attitude towards treatment.

Type
Short communication
Copyright
Copyright © Elsevier, Paris 1996

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References

American Psychiatric Association, third edition revisedDiagnostic and Statistical Manual of Mental Disorders Washington, DCAPA 1987Google Scholar
Anderson, WH, Kuehnle, JC, Catanzano, DMRapid treatment of acute psychosis Am J Psychiatry 1976 133 10761078Google ScholarPubMed
Burner, MRelations soignant-malade et modifications de la personnalité avec introduction appropriée d'un neuroleptique par voie intraveineuse dans la psychiatrie de crise Psychol Med 1975 7 19611970Google Scholar
Donlon, PTTupin, IPRapid ‘digitalization’ of decompensated schizophrenic patients with antipsychotic agents Am J Psychiatry 1974 131 310312CrossRefGoogle ScholarPubMed
Endicott, JSpitzer, RLFleiss, JLCohen, JThe Global Assessment Scale Arch Gen Psychiatry 1976 33 766771CrossRefGoogle ScholarPubMed
Gardos, GCole, JOMaintenance antipsychotic therapy: is the cure worse than the disease? Am J Psychiatry 1976 133 3236Google ScholarPubMed
Glick, IDHargreaves, WARaskin, MKutner, SShort versus long hospitalization: a prospective controlled study: results for schizophrenic inpatients Am J Psychiatry 1975 132 385390Google ScholarPubMed
Hansell, NWillis, GLOutpatient treatment of schizophrenia Am J Psychiatry 1977 134 10821086Google ScholarPubMed
Herz, JHEndicott, JSpitzer, RLBrief hospitalization of patients with families: initial results Am J Psychiatry 1975 132 413418Google ScholarPubMed
Herz, MIMelville, CRelapse in schizophrenia Am J Psychiatry 1980 137 801805Google Scholar
Kane, JMMarder, SRPsychopharmacologic treatment of schizophrenia Schizophren Bull 1993 19 287302CrossRefGoogle ScholarPubMed
May, PRRational treatment of an irrational disorder: What does the schizophrenic patient need? Am J Psychiatry 1976 1976 133 10081012Google ScholarPubMed
Solano, OASadow, TAnanth, JRapid tranquilization: a reevaluation Neuropsychobiology 1989 22 9096CrossRefGoogle Scholar
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