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Negative symptoms of schizophrenia in patients with acute and transient psychotic disorders
Published online by Cambridge University Press: 13 August 2021
Abstract
The ICD-10 acute and transient psychotic disorders (ATPD, F23) without symptoms of schizophrenia are considered predominantly reactive psychotic disorders or affective pathology. However, negative symptoms of schizophrenia may be revealed in some of these cases after the psychotic reduction.
To investigate the association between the developmental characteristics of psychosis and the negative symptoms detection after the psychotic reduction of ATPD without symptoms of schizophrenia.
68 adult inpatients with ATPD without symptoms of schizophrenia (F23.0) were examined. Negative symptoms were assessed with the PANSS negative symptom subscale (PANSS-NSS). The sample was divided into two groups: with PANSS-NSS score>14 (n=12) and with PANSS-NSS score≤14 (n=56), respectively. Clinical-psychopathological, psychometric and statistical methods were applied.
The results of the study are presented in Table 1.
Table 1. The ATPD developmental features | |||
Features | The 1st group (n=12) | The 2nd group (n=56) | Pearson’s contingency coefficient (C) |
Males | 7 (58,3%) | 37 (66,1%) | 0.062 |
Females | 5 (41,7%) | 19 (33,9%) | 0.062 |
Mean age of psychotic onset, years (М±m) | 24,9±10,5 | 30,8±10,2 | - |
Family history of schizophrenia* | 4 (33,3%) | 1 (1,8%) | 0.418 |
Poor premorbid social adaptation* | 5 (41,7%) | 0 | 0.520 |
Prodromal functional decline* | 9 (75,0%) | 4 (7,1%) | 0.550 |
Prodromal non-psychotic symptoms | 9 (75,0%) | 30 (53,6%) | 0.163 |
Associated acute stress | 4 (33,3%) | 27 (48,2%) | 0.113 |
*p<0,001
The probability of negative symptoms detection in ATPD without symptoms of schizophrenia is relatively strongly associated with the family history of schizophrenia, poor premorbid social adaptation and functional decline prior to the psychotic onset.
No significant relationships.
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- Information
- European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S802
- Creative Commons
- This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Copyright
- © The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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