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Negative symptoms in first episode schizophrenia: Results from the “parma early psychosis” program

Published online by Cambridge University Press:  13 August 2021

L. Pelizza ,
E. Leuci ,
D. Maestri ,
E. Quattrone ,
G. Paulillo ,
P. Pellegrini  and
S. Azzali
L. Pelizza*
Affiliation:
Department Of Mental Health, Azienda USL di Parma, Parma, Italy
E. Leuci
Affiliation:
Department Of Mental Health, Azienda USL di Parma, Parma, Italy
D. Maestri
Affiliation:
Department Of Mental Health, Azienda USL di Parma, Parma, Italy
E. Quattrone
Affiliation:
Department Of Mental Health, Azienda USL di Parma, Parma, Italy
G. Paulillo
Affiliation:
Department Of Mental Health, Azienda USL di Parma, Parma, Italy
P. Pellegrini
Affiliation:
Department Of Mental Health, Azienda USL di Parma, Parma, Italy
S. Azzali
Affiliation:
Department Of Mental Health, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
*
*Corresponding author.

Abstract

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Introduction

Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology.

Objectives

Aim of this study was to examine negative symptom structure in FES patients using the Positive and Negative Syndrome Scale (PANSS).

Methods

All 147 participants, aged 12–35 years, completed the PANSS and the Global Assessment of Functioning (GAF) scale. A principal component analysis with varimax rotation was performed to investigate PANSS negative symptom structure in the FES total sample.

Results

A 2-factor model (i.e. “Expressive Deficits” and “Asociality” dimensions) was identified. Only “Expressive Deficits” domain had a significant negative correlation with baseline GAF score.

Conclusions

This bipartite solution seems to be adequate to describe the phenomenological variety of negative symptoms experienced by FES individuals at the point of entry in early intervention services.

Disclosure

No significant relationships.

Keywords

psychopathologynegative symptomsschizophréniaearly psychosis
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S168 - S169
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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