Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-17T07:22:54.820Z Has data issue: false hasContentIssue false

Negative evidences in association between apolipoprotein E polymorphism and panic disorder

Published online by Cambridge University Press:  16 April 2020

S. Martínez-Barrondo*
Affiliation:
Department of Psychiatry, School of Medicine, University of Oviedo, Julian Clavería 6, 3, 33006Oviedo, Spain
P.A. Sáiz
Affiliation:
Department of Psychiatry, School of Medicine, University of Oviedo, Julian Clavería 6, 3, 33006Oviedo, Spain
B. Morales
Affiliation:
Laboratory of Molecular Genetics, Hospital Universitario Central de Asturias, Oviedo, Spain
M.P. García-Portilla
Affiliation:
Department of Psychiatry, School of Medicine, University of Oviedo, Julian Clavería 6, 3, 33006Oviedo, Spain
E. Coto
Affiliation:
Laboratory of Molecular Genetics, Hospital Universitario Central de Asturias, Oviedo, Spain
V. Álvarez
Affiliation:
Laboratory of Molecular Genetics, Hospital Universitario Central de Asturias, Oviedo, Spain
M.T. Bascarán
Affiliation:
Department of Psychiatry, School of Medicine, University of Oviedo, Julian Clavería 6, 3, 33006Oviedo, Spain
M. Bousoño
Affiliation:
Department of Psychiatry, School of Medicine, University of Oviedo, Julian Clavería 6, 3, 33006Oviedo, Spain
J. Bobes
Affiliation:
Department of Psychiatry, School of Medicine, University of Oviedo, Julian Clavería 6, 3, 33006Oviedo, Spain
*
*Corresponding author. E-mail address:[email protected] (S. Martínez-Barrondo).
Get access

Abstract

The aim is to investigate the association between apolipoprotein E (ApoE) and panic disorder (PD). Genotyping 92 PD patients [Diagnostic Statistic Manual IV (DSM IV) criteria] and 174 controls no differences were found between both groups. Variation in the ApoE-gene was not associated with the development of PD.

Type
Short communication
Copyright
Copyright © Elsevier SAS 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Agargun, MYAlgun, ESekeroglu, RKara, HTarakcioglu, MLow cholesterol levels in patients with panic disorder: the association with major depression. J. Affect. Disord. 1998;50:2932.CrossRefGoogle Scholar
Agargun, MYKara, HAlgun, ESekeroglu, RTarakcioglu, MHigh cholesterol levels in patients with sleep panic. Biol. Psychiatry 1996;40:10641065.CrossRefGoogle ScholarPubMed
Bajwa, WKAsnis, GMSanderson, WCIrfan, Avan Praag, HMHigh cholesterol levels in patients with panic disorder. Am. J. Psychiatry 1992;149:376378.Google ScholarPubMed
Bassett, CNMontine, TJLipoproteins and lipid peroxidation in Alzheimer's disease. J. Nutr. Health Aging 2003;7:2429.Google ScholarPubMed
Dantendorfer, KPrayer, DKramer, JAmering, MBaischer, WBerger, Pet al.High frequency of EEG and MRI brain abnormalities in panic disorder. Psychiatry Res. 1996;68:4153.CrossRefGoogle ScholarPubMed
Feder, RHigh cholesterol levels in patients with panic disorder. Am. J. Psychiatry 1993;150:527.Google ScholarPubMed
Hayward, CTaylor, CBRoth, WTKing, RAgras, WSPlasma lipid levels in patients with panic disorder or agoraphobia. Am. J. Psychiatry 1989;146:917919.Google ScholarPubMed
Massana, GSerra-Grabulosa, JMSalgado-Pineda, PGasto, CJunque, CMassana, JMercader, JMParahippocampal gray matter density in panic disorder: a voxel-based morphometric study. Am. J. Psychiatry 2003;160:566568.CrossRefGoogle ScholarPubMed
Michikawa, MThe role of cholesterol in pathogenesis of Alzheimer's disease: dual metabolic interaction between amyloid beta-protein and cholesterol. Mol. Neurobiol. 2003;27:112.CrossRefGoogle ScholarPubMed
Morrow, JDMcManus, KTait, GRBellavance, FChrapko, WLara, N, et al.Pentagastrin-induced release of free fatty acids in healthy volunteers and patients with panic disorder: effect of pretreatment with ethinyl estradiol. J. Psychiatry Neurosci. 2003;28:127133.Google ScholarPubMed
Papakostas, GIÖngür, DIosifescu, DVMischoulon, DFava, MCholesterol in mood and anxiety disorders: review of the literature and new hypotheses. Eur. Neuropsychopharmacol. 2004;14:135142.CrossRefGoogle ScholarPubMed
Petanceska, SSDeRosa, SSharma, ADiaz, NDuff, KTint, SG, et al.Changes in a apolipoprotein E expression in response to dietary and pharmacological modulation of cholesterol. Mol. Neurosci. 2003;20:395406.CrossRefGoogle Scholar
Pitas, REBoyles, JKLee, SHHiu, DWeisgraber, KHLipoproteins and their receptors in the central nervous system. J. Biol. Chem. 1987;262:1435214360.Google ScholarPubMed
Puglielli, LTanzi, REKovacs, DMAlzheimer's disease: the cholesterol connection. Nat. Neurosci. 2003;6:345351.CrossRefGoogle ScholarPubMed
Sáiz, PAMorales, BG-Portilla, MPÁlvarez, VCoto, EFernández, JM, et al.Apolipoprotein E genotype and schizophrenia: further negative evidence. Acta Psychiatr. Scand. 2002;105:7175.Google ScholarPubMed
Shiori, TFujii, KSomeya, TTakahashi, SFrequency distribution of serum cholesterol levels in patients with panic disorder: comparison with normal controls. Psychiatry Clin. Neurosci. 1998;52:601604.CrossRefGoogle Scholar
Shioiri, TFujii, KSomeya, TTakahashi, SSerum cholesterol levels and panic symptoms in patients with panic disorder: a preliminary study. J. Affect. Disord. 2000;58:167170.CrossRefGoogle ScholarPubMed
Tancer, MEStein, MBMoul, DEUhde, TWNormal serum cholesterol in panic disorder. Biol. Psychiatry 1990;27:99101.CrossRefGoogle ScholarPubMed
Tsukamoto, KTangirala, RKChun, SUsher, DPure, ERader, DJHepatic expression of apolipoprotein E inhibits progression of atherosclerosis without reducing cholesterol levels in LDL receptor-deficient mice. Mol. Ther. 2000;1:189194.CrossRefGoogle ScholarPubMed
Weeber, EJBeffert, UJones, CChristian, JMForster, ESweatt, JD, et al.Reelin in ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning. J. Biol. Chem. 2002;277:3994439952.CrossRefGoogle ScholarPubMed
Wenham, PRPrice, WHBlandell, GApolipoprotein E genotyping by one-stage PCR. Lancet 1991;337:11581159.CrossRefGoogle ScholarPubMed
World Medical Association. Declaration of Helsinki. Recommendations guiding physicians in biomedical research involving human subject. Amended by 41st World Medical Assembly, Hong Kong, 1989.Google Scholar
Submit a response

Comments

No Comments have been published for this article.