Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-23T03:36:39.989Z Has data issue: false hasContentIssue false

Mood disorders with delusions versus schizophrenic disorders with delusions. Second phase of a longitudinal study of a cohort of adolescent psychiatric inpatients with delusions

Published online by Cambridge University Press:  16 April 2020

O Halfon
Affiliation:
Fondation Santé des Étudiants de France, Clinique Médico-Psychologique, Neufmoutiers-en-Brie
MC Mouren-Simeoni
Affiliation:
Hôpital Necker-Enfants Malades, Paris
F Radat
Affiliation:
Hôpital Saint-Antoine, Paris
E Albert
Affiliation:
Hôpital Robert Debré, Paris, France
V Nahama
Affiliation:
Fondation Santé des Étudiants de France, Clinique Médico-Psychologique, Neufmoutiers-en-Brie
M Dugas
Affiliation:
Hôpital Robert Debré, Paris, France
Get access

Summary

The prognostic significance of an index episode of affective disorder with delusions was assessed in a longitudinal study of a cohort of adolescent psychiatric inpatients (n = 43). Part I of a study has been reported in a previous article. Initial assessmentdata (anamnestic variables, clinical assessment) did not discriminate between onset of affective disorder and schizophrenia. Part II of the study provides a longitudinal perspective of the cohort's diagnostic and life adjustment: diagnoses of schizophrenia increased, schizophreniform disorders disappeared, affective disorders were stable and a schizo-affective category emerged. Patients in the schizophrenic category had severely impaired life adjustment, while the level of functioning in unipolar and bipolar patients was consistently satisfactory. Compared to the initial diagnosis, the cohort showed a tendency to develop into schizophrenia. It is too early to affirm that every adolescent with delusional symptoms at onset will later develop schizophrenia, however, this risk appears real.

Type
Original article
Copyright
Copyright © Elsevier, Paris 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abrams, RTaylor, MA (1976) Mania and schizo-affective disorder manic type: a comparison. Am J Psychiatry 133, 14451447CrossRefGoogle ScholarPubMed
American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders. 3rd edn (DSM III) Washington DCGoogle Scholar
American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders. 3rd edn revised (DSM III-R) Washington DCGoogle Scholar
Baron, MGruen, EAsnis, L (1982) Schizoaffective illness schizophrenia and affective disorders: morbidity risk and genetic transmission. Acta Psychiatr Scand 65, 253262CrossRefGoogle ScholarPubMed
Breier, ASchreiber, JDyer, JPicken, D (1991) National institute of mental health longitudinal study of chronic schizophrenia. Arch Gen Psychiatry 48, 239246CrossRefGoogle ScholarPubMed
Carone, BHarrow, MWestermeyer, J (1991) Posthospital course and outcome in schizophrenia. Arch Gen Psychiatry 48, 247253CrossRefGoogle Scholar
Chambers, WPuig-Antich, JHirsch, MPaez, PAnbrosini, PTabrizi, MDavies, M (1985) The assessment of affective disorders in children and adolescents by semistructured interview: test-retest reliability of the KSADS. Arch Gen Psychiatry 42, 696702CrossRefGoogle Scholar
Coryell, WTsuang, MT (1985) Major depression with mood congruent or mood incongruent psychotic features: Outcome after 40 years. Am J Psychiatry 142, 479482Google ScholarPubMed
Endicott, JSpitzer, R (1978) A diagnostic interview. The schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 35, 773782CrossRefGoogle Scholar
Fowler, RCMcCabe, MECadoret, RJ (1972) The validity of good prognosis schizophrenia. Arch Gen Psychiatry 26, 182185CrossRefGoogle ScholarPubMed
Fowler, RC (1978) Remitting schizophrenia as a variant of affective disorder. Schizophr Bull 4, 6877CrossRefGoogle ScholarPubMed
Grossman, LSHarrow, MFudala, JLMeltzer, HY (1984) The longitudinal course of schizoaffective disorder. Nerv Ment Dis 172, 140149CrossRefGoogle Scholar
Halfon, OAlbert, EMouren-Simeoni, MCDugas, M (1990) Troubles thymiques dëlirants versus troubles schizophreniques délirants: à propos de l'étude d'une cohorte d'adolescents délirants. 1. Antécédents et sémiologie. Psychiatr Psychobiol 5, 1322Google Scholar
Kendell, RE (1986) The Relationship of Schizoaffective Illnesses to Schizophrenic and Affective Disorders in Schizoaffective Psychoses. Springer, New YorkGoogle Scholar
McCabe, MSFowler, RCCadoret, RJ (1972) Symptom differences in schizophrenia with good and poor prognosis. Am J Psychiatry 128, 12391243CrossRefGoogle ScholarPubMed
McGlashan, TH (1984) The Chesnut Lodge follow-up study. II. Long term outcome of schizophrenia and the affective disorders. Arch Gen Psychiatry 41, 586601CrossRefGoogle Scholar
Maj, MPerris, C (1985) An approach to the diagnosis and classification of schizoaffective disorders for research purposes. Act Psychiatr Scand 72, 405413CrossRefGoogle ScholarPubMed
Mendlewicz, JLinkowski, PWilmotte, J (1980) Relationship between schizoaffective illness and affective disorders or schizophrenia. J Affective Disord 2, 289302CrossRefGoogle ScholarPubMed
Pope, HGLipinski, JF (1978) Diagnosis in schizophrenia and manic-depressive illness: a reassessment of the specificity of ‘schizophrenic’ symptoms in the light of current research. Arch Gen Psychiatry 122, 811828CrossRefGoogle Scholar
Pope, HGLipinski, JFCohen, BMAxelrod, DT (1980) Schizoaffective disorder: an invalid diagnosis? A comparison of schizoaffective disorder, schizophrenia and affective disorder. Am J Psychiatry 137, 921927Google ScholarPubMed
Pope, HG Jr (1981) Differential diagnosis of acute psychotic disorders. In: Directions in Psychiatry (Flach, FF ed) Hatherleigh Co, New YorkGoogle Scholar
Robbins, EGuze, SB (1970) Establishment of diagnostic validity in psychiatric illness, its applications to schizophrenia. Am J Psychiatry 126, 983987CrossRefGoogle Scholar
Rosenthal, NRosenthal, LStallone, F (1980) Toward the validation of RDC schizoaffective disorder. Arch Gen Psychiatry 37, 804810CrossRefGoogle ScholarPubMed
Stephens, JHAstrup, CMangrum, JC (1966) Prognostic factors in recovered and deteriorated schizophrenics. Am J Psychiatry 122, 11161121CrossRefGoogle ScholarPubMed
Taylor, MAAbrams, R (1975) Manic depressive illness and good prognosis schizophrenia. Am J Psychiatry 132, 741742Google ScholarPubMed
Tsuang, MTSimpson, JCFlemming, JA (1986) Diagnostic Criteria for Subtyping Schizoaffective Disorder in Schizoaffective Disorder. Springer, New YorkGoogle Scholar
Vaillant, GE (1964) Prospective prediction of schizophrenic remission. Arch Gen Psychiatry 11, 509518CrossRefGoogle ScholarPubMed
Williams, PVMcGlashan, TH (1987) Schizoaffective psychosis. 1. Comparative longterm outcome. 2. Manic bipolar and depressive subtype. Arch Gen Psychiatry 44, 130139CrossRefGoogle Scholar
Submit a response

Comments

No Comments have been published for this article.