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Maternal autoimmune diseases and mental disorders in children and adolescents

Published online by Cambridge University Press:  19 July 2023

Z. Elmaataoui ,
H. Belhadga  and
H. Kisra
Z. Elmaataoui*
Affiliation:
Hospital Ar-Razi of sale, Sale, Morocco
H. Belhadga
Affiliation:
Hospital Ar-Razi of sale, Sale, Morocco
H. Kisra
Affiliation:
Hospital Ar-Razi of sale, Sale, Morocco
*
*Corresponding author.

Abstract

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Introduction

The influence of maternal autoimmunity mediators on child development and brain function has been the subject of several studies. Clinically, most have focused on the association between maternal autoimmunity and the diagnosis of autism in children. On the other hand, data are rarer concerning the rest of the mental disorders and mainly, they are obtained from small cohorts.

Objectives

The aim of this study is to discuss the association between the presence of autoimmune pathology in the mother and the development of mental disorders in the child

Methods

we conducted our study through a descriptive study of six clinical cases.

Results

80 % the patients treated were male

57% had a characterized depressive disorder

34% had ADHD

9 % had ASD

Conclusions

Maternal autoimmune diseases were associated with increased mental disorders in children. These results suggest a possible shared genetic vulnerability between the two conditions or a potential role of maternal immune activation in the expression of neurodevelopmental disorders in children.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 66 , Special Issue S1: Abstracts of the 31st European Congress of Psychiatry , March 2023 , pp. S280
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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