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Major symptoms and differential diagnosis of neuroleptic malignant syndrome: three case reports

Published online by Cambridge University Press:  16 April 2020

C. Védie ,
F. Poinso ,
F. Hemmi  and
B. Rivet
C. Védie*
Affiliation:
C.H. Valvert, Bd des libérateurs, 13391Marseilles cedex 11, France
F. Poinso
Affiliation:
Hôpital Ste Marguerite, 13009Marseilles, France
F. Hemmi
Affiliation:
Hôpital La Colombière, 39 av. Ch. Flahaut, 34000Montpellier, France
B. Rivet
Affiliation:
C.H. Valvert, Bd des libérateurs, 13391Marseilles cedex 11, France
*
*Correspondence and reprints
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Summary

The authors describe the cases of three patients presenting a major extrapyramidal symptom with rising CPK, inconstant hyperthermia and autonomic dysfunction. Through a brief review of the literature, the authors question the unity of the malignant syndrome. If hypertonia is quite constant, the rise in the seric CPK is aspecific and hyperthermia is inconstant.

Keywords

CPKhyperthermianeurolepticNMS
Type
Original Article
Information
European Psychiatry , Volume 15 , Issue 5 , August 2000 , pp. 334 - 337
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2000

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References

Addonizio, GSusman, V.LRoth, S.DSymptoms of neuroleptic malignant syndrome in 82 consecutive inpatients Am J Psychiatry 143 1986 1587–1590Google ScholarPubMed
Addonizio, GSusman, V.LRoth, S.DDiagnosing and defining of NMS [letter] Am J Psychiatry 144 1987 137137Google Scholar
Ayd, F.JFatal hyperpyrexia during chlorpromazine therapy J Clin Exp Psychopathol 17 1956 189–192Google ScholarPubMed
Benoit, PMelandri, PDupont, DGrimard, DMaestracci, PLe syndrome malin des neuroleptiques Concours Médical 103 1981 1063–1080Google Scholar
Caroff, S.NThe neuroleptic malignant syndrome J Clinic Psychiatry 41 1980 79–83Google ScholarPubMed
Delay, JPichot, PLemperiere, TUn neuroleptique majeur non phénothiazine et non réserpinique, l'halopéridol dans le traitement des psychoses Ann Méd Psychol 118 1960 145–152Google Scholar
Levenson, LNeuroleptic malignant syndrome Am J Psychiatry 142 1985 1137–1145Google ScholarPubMed
Levinson, D.FSimpson, G.MNeuroleptic-Induced extrapyramidal symptoms with fever Arch Gen Psychiatry 43 1986 839–848CrossRefGoogle ScholarPubMed
Mann, S.CCaroff, S.NBleir, H.RWelz, W.KKling, M.AHayashida, MLethal catatonia Am J Psychiatry 143 1986 1374–1381Google ScholarPubMed
Pope, H.GKeck, P.EMcElroy, S.LFrequency and presentation of neuroleptic malignant syndrome in a large psychiatric hospital Am J Psychiatry 143 1986 1227–1233Google Scholar
Sullivan, C.FA possible variant of neuroleptic malignant syndrome Br J Psychiatry 151 1987 689–690CrossRefGoogle ScholarPubMed
Thase, M.EShostak, MRhabdomyolysis complicating rapid intramuscular neuroleptization J Clin Psychopharmacol 4 1984 46–4810.1097/00004714-198402000-00008CrossRefGoogle ScholarPubMed
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