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Local and exhaustive study of transmission of detected psychopathological dimensions in family groups in the “albanova” area

Published online by Cambridge University Press:  13 August 2021

C. Serritella ,
A. Russo ,
G. Rossi ,
M. Paolino ,
M. Baldascino ,
H. Del Vecchio ,
M. Cimmino  and
T. Salvati
C. Serritella*
Affiliation:
Department Of Mental Health (dsm), Mental Health Operational Unit (Uosm) Of San Cipriano D’aversa, Caserta, Italy
A. Russo
Affiliation:
Department Of Economics, University Of Studies Of Campania Luigi Vanvitelli, Caserta, Italy
G. Rossi
Affiliation:
Department Of Mental Health (dsm), Mental Health Operational Unit (Uosm) Of San Cipriano D’aversa, Caserta, Italy
M. Paolino
Affiliation:
Department Of Mental Health (dsm), Mental Health Operational Unit (Uosm) Of San Cipriano D’aversa, Caserta, Italy
M. Baldascino
Affiliation:
Department Of Mental Health (dsm), Mental Health Operational Unit (Uosm) Of San Cipriano D’aversa, Caserta, Italy
H. Del Vecchio
Affiliation:
Department Of Mental Health (dsm), Mental Health Operational Unit (Uosm) Of San Cipriano D’aversa, Caserta, Italy
M. Cimmino
Affiliation:
Cnr Napoli, Genetics and biophysics “Adriano Buzzati Traverso”, Caserta, Italy
T. Salvati
Affiliation:
Chair Of Evolutionary Age, University Of Studies Of Naples Suor Orsola Benincasa, Caserta, Italy
*
*Corresponding author.

Abstract

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Introduction

It is not known with certainty how different phenotypes are transmitted in groups of families divided into three generations.

Objectives

Having meticulously searched for terms of psychopathogic lexicon that best translated the sterile categorical diagnosis, we obtained three dimensional groups for all six families in the three generations.

Methods

We calculated the frequencies and percentages of the three dimensional groups for the three generations of families based on sex.

Results

The chi-square TEST attests a p-value = 0.049, statistically significant for the dimensional group “A”. (Tab. 3)

Conclusions

The genetics, and above all the epigenetics, of the phenotypes are periodically transmitted in group “A” and group “C” in the female and male sex. (Graphs 2.1.1 and 2.3.1) Different phenotypes indicate that the complexity of the interactions of the regulatory mechanisms of genes with the environment is extremely significant for the group with the most severe psychiatric pathology.

Keywords

PhenotipegeneticsepigeneticsPsychopatological
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S319 - S320
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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