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Lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. A pragmatic clinical trial

Published online by Cambridge University Press:  01 September 2022

B. Fernández-Abascal ,
P. Suárez-Pinilla ,
C. Cobo-Corrales ,
B. Crespo-Facorro  and
M. Suarez-Pinilla
B. Fernández-Abascal*
Affiliation:
University Hospital Marqués de Valdecilla, IDIVAL Hospital, Department Of Psychiatry, Santander, Spain
P. Suárez-Pinilla
Affiliation:
University Hospital Marqués de Valdecilla IDIVAL, Department Of Psychiatry, Santander, Spain
C. Cobo-Corrales
Affiliation:
University Cantabria, School Of Education, Santander, Spain
B. Crespo-Facorro
Affiliation:
University Hospital Virgen del Rocío - IBiS, Department Of Psychiatry,school Of Medicine, Sevilla, Spain
M. Suarez-Pinilla
Affiliation:
University College of London, Department Of Neurodegenerative Disease, Institute Of Neurology, London, United Kingdom
*
*Corresponding author.

Abstract

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Introduction

Patients with Schizophrenia Spectrum Disorders (SSD) often lead unhealthy lifestyles with higher prevalence of obesity and unfavourable cardiometabolic parameters with less life expectancy and often worse quality of life compared with general population.

Objectives

Evaluate the effectiveness of a combined intervention of exercise and psychoeducation in 48 SSD outpatients with metabolic syndrome (MetS), treated with second-generation antipsychotics and also aimed to explore if the effect persisted in a long-term follow-up of 24 months.

Methods

The intervention included a 12-week aerobic exercise program and a session of lifestyle psychoeducation. Effectiveness was measured in terms a wide range of outcomes involving physical and psychological health, functioning, quality of life, physical activity and changes in motivation to exercise in the context of the self-determination theory.

Results

The active intervention group showed benefits after Bonferroni correction over clinical global impression, identified motivation to exercise and changes of physical activity pattern. Maintenance of effects after 24 months of follow-up was observed for identified regulation to exercise and also for negative symptoms of psychosis (Table). Table. Effects assigned-group/time-over *p≤0.05 **p≤0.01.

Variables12weeks24monthsTimeGroupxtimeGroupx timex gender
ppppp
HDL (mg/dl)0.021*
Negative Syndrome Scale0.044*0.004**
BREQ-2- Extrinsic regulation0.008**0.004**
-External0.026*
-Introyected0.038*
-Identified0.018*0.015*0.003**0.002**
BREQ-2-Intrinsic regulation0.005**0.004**
Pedometer (steps/day)0.001**0.006**

Conclusions

A combined intervention on SSD outpatients with MetS showed effectiveness over several clinical parameters and functioning. Therefore, should be considered an essential part of the integral treatment in mental health services for SSD patients.

Disclosure

No significant relationships.

Keywords

non-affective psychosis,exerciseQuality of Lifecardiometabolic risk
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S130 - S131
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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