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Life events exposure before a treated major depressive episode depends on the number of past episodes

Published online by Cambridge University Press:  16 April 2020

Emmanuelle Corruble ,
Bruno Falissard  and
Philip Gorwood
Emmanuelle Corruble*
Affiliation:
Department of Psychiatry, Assistance Publique-Hôpitaux de Paris, Bicêtre University Hospital, INSERM U 669, Paris XI University, 78, rue du General Leclerc, 94230 Le Kremlin Bicêtre, France
Bruno Falissard
Affiliation:
Department of Biostatistics and Public Health, Assistance Publique-Hôpitaux de Paris, Paul Brousse Hospital, INSERM U669, Paris XI University, 94800 Villejuif, France
Philip Gorwood
Affiliation:
Department of Psychiatry, Assistance Publique-Hôpitaux de Paris, Louis Mourier Hospital, INSERM U675 Paris VII University, 92700 Colombes, France
*
*Corresponding author. E-mail address: [email protected] (E. Corruble).
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Abstract

A cross-sectional survey investigated the relationship between the number of previous depressive episodes and life events, testing the kindling hypothesis, in a sample of 13,377 treated patients with unipolar depression. A linear decline of average life events exposure is observed for more frequent past episodes, even when age, gender and severity are taken into account.

Keywords

Recurrent depressionLife eventsKindling
Type
Original article
Information
European Psychiatry , Volume 21 , Issue 6 , September 2006 , pp. 364 - 366
Copyright
Copyright © Elsevier SAS 2006

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References

Holmes, T.H., Rahe, R.H.The social readjustment rating scale J. Psychosom. Res. 1967; 11:213–217.CrossRefGoogle ScholarPubMed
Kendler, K.S., Thornton, L.M., Gardner, C.O.Stressful life events and previous episodes in the etiology of major depression in women. An evaluation of the “kindling” hypothesis Am. J. Psychiatry 2000; 157:1243–1251.CrossRefGoogle ScholarPubMed
Kendler, K.S., Thornton, L.M., Gardner, C.O.Genetic risk, number of previous depressive episodes, and stressful life events in predicting onset of major depression Am. J. Psychiatry 2001; 158:582–586.CrossRefGoogle ScholarPubMed
Lecrubier, Y., Sheehan, D.V., Weiller, E., Amorim, P., Bonora, I., Harnett-Sheehan, K.et al.The Mini International Neuropsychiatric Interview (MINI). A short diagnostic structured interview: reliability and validity according to the CIDI Eur. Psychiatry 1997; 12:224–230.CrossRefGoogle Scholar
Monroe, S.M., Harkness, K.L.Life stress, the “kindling” hypothesis, and the recurrence of depression: considerations from a life stress perspective Psychol. Rev. 2005; 112:417–445.CrossRefGoogle ScholarPubMed
Montgomery, S., Asberg, M.A new scale designed to be sensitive to change Br. J. Psychiatry 1979; 134:382–389.CrossRefGoogle ScholarPubMed
Olsen, L.R., Mortensen, E.L., Bech, P.Prevalence of major depression and stress indicators in the Danish general population Acta Psychiatr. Scand. 2004; 109:96–103.CrossRefGoogle ScholarPubMed
Sheline, Y., Sanghavi, M., Mintun, M., Gado, M.Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression J. Neurosci. 1999; 19:5034–5043.CrossRefGoogle Scholar
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