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Life events and changes in the course of depression in young adults

Published online by Cambridge University Press:  16 April 2020

Robert H. Friis ,
Hans-Ulrich Wittchen ,
Hildegard Pfister  and
Roselind Lieb
Robert H. Friis
Affiliation:
Department of Health Science, California State University, Long Beach, CA, USA
Hans-Ulrich Wittchen
Affiliation:
Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology, Kraepelinstr. 2, 80804, Munich, Germany Department of Clinical Psychology and Psychotherapy, Technical University Dresden, Dresden, Germany
Hildegard Pfister
Affiliation:
Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology, Kraepelinstr. 2, 80804, Munich, Germany
Roselind Lieb*
Affiliation:
Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology, Kraepelinstr. 2, 80804, Munich, Germany
*
*Corresponding author. E-mail address:[email protected](R. Lieb).
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Summary

Background.

Few community-based studies have examined the impact of life events, life conditions and life changes on the course of depression. This paper examines associations of life events on depressive symptom onset, improvement, and stability.

Methods.

Direct interview data from the Early Developmental Stages of Psychopathology Study (EDSP), a 4–5 year prospective-longitudinal design based on a representative community sample of adolescents and young adults, aged 14–24 years at baseline, are used. Life events were measured using the Munich Event-Questionnaire (MEL) consisting of 83 explicit items from various social role areas and subscales for the assessment of life event clusters categorized according to dimensions such as positive and negative and controllable and uncontrollable. Depressive disorders were assessed with the DSM-IV version of the Munich Composite Diagnostic Interview (M-CIDI). Multiple logistic regression analyses examined the effects of 22 predictors on the course of depression (onset, improvement, stability).

Results.

Younger age, low social class, negative and stressful life events linked to the family were associated with increased risk of new onset of depression. Anxiety was a significant independent predictor of new onset of depression. Absence of stressful school and family events was related to improvement in depression. The weighted total number of life events predicted stable depression.

Conclusions.

The association between life events and the course of depression appears to vary according to the outcome being examined, with different clusters of life events differentially predicting onset, improvement, and stability.

Keywords

Life eventsMajor depressionEpidemiologyYoung adultsPrevalenceIncidence
Type
Original article
Information
European Psychiatry , Volume 17 , Issue 5 , September 2002 , pp. 241 - 253
Copyright
Copyright © European Psychiatric Association 2002

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References

Ferguson, ELawrence, CMatthews, G. Associations between primary appraisal and life-events while controlling for depression. Br J Clin Psychol 2000;39:143–55.CrossRefGoogle Scholar
Butow, PNHiller, JEPrice, MAThackway, SVKricker, ATennant, CC. Epidemiological evidence for a relationship between life events, coping style, and personality factors in the development of breast cancer. J Psychosomatic Res 2000;49(3):169–81.Google ScholarPubMed
Leserman, JPetitto, JMGolden, RNGaynes, BNGu, HBPerkins, DO et al. Impact of stressful life events, social support, coping, and cortisol on progression to AIDS. Am J Psychiatry 2000;157(8):1221–8.Google ScholarPubMed
Peterson, MGEAllegrante, JPAugurt, ARobbins, LMacKenzie, CRCornell, CN. Major life events as antecedents to hip fracture. J Trauma-Injury Infect Crit Care 2000;48(6):1096–100.CrossRefGoogle ScholarPubMed
Brown, GWHarris, TO. Social origins ofdepression: a study of psychiatry disorder in women. New York: Free Press; 1978.Google Scholar
Kendler, KSKessler, RCWalters, EEMacLean, CNeale, MCHeath, AC et al. Stressful life events, genetic liability, and onset of an episode of major depression in women. Am J Psychiatry 1995;152:833–42.Google ScholarPubMed
Billings, ACronkite, RMoos, R. Social environment factors in unipolar depression: comparisons of depressed patients and nondepressed controls. J Abnormal Psychol 1983;93:119–33.CrossRefGoogle Scholar
Blazer, DHughes, DGeorge, LK. Stressful life events and the onset of a generalized anxiety syndrome. Am J Psychiatry 1987;144:1178–85.Google ScholarPubMed
Murphy, DAMoscicki, ABVermund, SHMuenz, LR. Psychological distress among HIV+ adolescents in the REACH study: effects of life stress, social support, and coping. J Adoles Health 2000;27(6):391–8.CrossRefGoogle ScholarPubMed
Kessler, RC. The effects of stressful life events on depression. Ann Rev Psychol 1997;48:191–214.Google ScholarPubMed
Wittchen, HU. Chronic difficulties and life events in the long-term course of affective and anxiety disorders: results from the Munich-follow-up study. In: Angermeyer, MC editor. From social class to social stress – New developments in psychiatric epidemiology. Berlin: Springer; 1987. p. 176–96.Google Scholar
Mundt, CReck, CBackenstrass, MKronmuller, KFiedler, P. Reconfirming the role of life events for the timing of depressive episodes. A two-year prospective follow-up study. J Affect Disorders 2000;59 (1):23–30.CrossRefGoogle ScholarPubMed
Holmes, THRahe, RH. The social adjustment scale. J Psychosomatic Res 1967;11:213–8.CrossRefGoogle Scholar
Paykel, ES. Life events, social support and depression. Acta Psychiatrica Scandinavica 1994;377 (Suppl):50–8.CrossRefGoogle ScholarPubMed
Bifulco, ABernazzani, OMoran, PMBall, C. Lifetime stressors and recurrent depression: preliminary findings of the Adult Life Phase Interview (ALPHI). Social Psychiatry and Psychiatric Epidemiology 2000;35(6):264–75.CrossRefGoogle Scholar
Brown, GWBifulco, AHarris, TO. Life events, vulnerability and onset of depression: some refinements. Br J Psychiatry 1987;150:30–42.CrossRefGoogle ScholarPubMed
Goodyer, IMHerbert, JPamplin, AAltham, PME. First-episode major depression in adolescents. Affective, cognitive and endocrine characteristics of risk status and predictors of onset. Br J Psychiatry 2000;176:142–9.Google ScholarPubMed
Eley, TCStevenson, J. Specific life events and chronic experiences differentially associated with depression and anxiety in young twins. J Abnormal Child Psychol 2000;28:383–94.CrossRefGoogle ScholarPubMed
Shrout, PELink, BDohrenwend, BSkodol, AE. Characterizing life events as risk factors for depression: the role of fateful loss events. J Abnormal Psychol 1989;98:460–7.CrossRefGoogle ScholarPubMed
Kendler, KSKarkowski, LMPrescott, CA. Stressful life events and major depression: risk period, long-term contextual threat, and diagnostic specificity. Journal of Nervous Mental Disease 1998;186:661–9.CrossRefGoogle ScholarPubMed
Kendler, KSKarkowski, LMPrescott, CA. Causal relationship between stressful life events and the onset of major depression. Am J Psychiatry 1999;156:837–41.CrossRefGoogle ScholarPubMed
Kendler, KSKarkowski-Shuman, L. Stressful life events and genetic liability to major depression: genetic control of exposure to the environment? Psychological Med 1997;27:539–47.CrossRefGoogle ScholarPubMed
Farmer, AHarris, TRedman, KSadler, SMahmood, AMcGuffin, P. Cardiff depression study. A sib-pair study of life events and familiality in major depression. Br J Psychiatry 2000;176:150–5.Google ScholarPubMed
Faravelli, CSacchetti, EAmbonetti, AConte, GPallanti, SVita, A. Early life events and affective disorder revisited. Br J Psychiatry 1986;148:288–95.Google Scholar
Kendler, KSThornton, LMGardner, CO. Stressful life events and previous episodes in the etiology of major depression in women: an evaluation of the “kindling” hypothesis. Am J Psychiatry 2000;157(8):1243–51.CrossRefGoogle ScholarPubMed
Holahan, CMoos, R. Life stressors, personal and social resources, and depression: a 4-year structural model. J Abnormal Psychol 1991;100:31–8.CrossRefGoogle ScholarPubMed
Maciejewski, PKPrigerson, HGMazure, CM. Self-efficacy as a mediator between stressful life events and depressive symptoms. Differences based on history of prior depression. Br J Psychiatry 2000;176:373–8.CrossRefGoogle ScholarPubMed
Wade, TDKendler, KS. Absence of interactions between social support and stressful life events in the prediction of major depression and depressive symptomatology in women. Psychological Med 2000;30:965–74.CrossRefGoogle ScholarPubMed
Kessler, RCKendler, KSHeath, ANeale, MCEaves, LJ. Social support, depressed mood, and adjustment to stress: a genetic epidemiologic investigation. J Personality Social Psychol 1992; 62:257–72.CrossRefGoogle ScholarPubMed
Wittchen, HUPerkonigg, ALachner, GNelson, CB. Early developmental stages of psychopathology study (EDSP): objectives and design. Eur Addiction Res 1998;4(1–2):18–27.CrossRefGoogle ScholarPubMed
Lieb, RIsensee, BSydow, KvonWittchen, HU. The early developmental stages of psychopathology study (EDSP): a methodological update. Eur Addiction Res 2000;6:170–82.Google ScholarPubMed
Wittchen, HUNelson, GBLachner, G. Prevalence of mental disorders and psychosocial impairments in adolescents and young adults. Psychological Med 1998;28:109–26.CrossRefGoogle ScholarPubMed
Wittchen, HUPfister, H editors. DIA-X-Interviews: Manual für Screening-Verfahren und Interview; Interviewheft Längsschnittuntersuchung (DIA-X-Lifetime); Ergänzungsheft (DIA-X-Lifetime); Interviewheft Querschnittuntersuchung (DIA-X-12 Monate); Ergänzungsheft (DIA-X-12Monate); PC-Programm zur Durchführung des Interviews (Längs- und Querschnittuntersuchung);Auswertungsprogramm. Frankfurt: Swets & Zeitlinger; 1997.Google Scholar
World Health Organisation. Composite International Diagnostic Interview (CIDI): (a) CIDI-interview (version 1.0), (b) CIDI-user manual, (c) CIDI-training manual (d) CIDI-computer programs. Geneva: World Health Organisation; 1990.Google Scholar
American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 4th ed. Washington DC: APA; 1994.Google Scholar
World Health Organization. ICD-10, Chapter V, Mental and Behavioral Disorders (including disorders of psychological development). Diagnostic Criteria for Research. Draft for Field Trials. Geneva: World Health Organization; 1991.Google Scholar
Wittchen, HULieb, RSchuster, POldehinkel, T. When is onset? Investigations into early developmental stages of anxiety and depressive disorders. In: Rapoport, JL editor. Childhood onset of “adult” psychopathology, clinical and research advances. Washington: American Psychiatric Press; 1999. p. 259–302.Google Scholar
Höfler, MLieb, RPerkonigg, ASchuster, PSonntag, HWittchen, HU. Covariates of cannabis use progression in a representative population sample of adolescents: a prospective examination of vulnerability and risk factors. Addiction 1999; 94(11):1679–94.Google Scholar
Lachner, GWittchen, HUPerkonigg, AHolly, ASchuster, PWunderlich, U et al. Structure, content and reliability of the Munich-Composite International Diagnostic Interview (M-CIDI). Substance use sections. European Addiction Research 1998;4(1–2):28–41.Google ScholarPubMed
Reed, VGander, FPfister, HSteiger, ASonntag, HTrenk-walder, C et al. To what degree the Composite International Diagnostic Interview (CIDI) correctly identifies DSM-IV disorders? Testing validity issues in a clinical sample. Int J Meth Psychiatric Res 1998;7(3):142–55.CrossRefGoogle Scholar
Wittchen, HULachner, GWunderlich, UPfister, H. Test-retest reliability of the computerized DSM-IVversion ofthe Munich-Composite International Diagnostic Interview (M-CIDI). Social Psychiatry and Psychiatric Epidemiology 1998;33:568–78.CrossRefGoogle Scholar
Oldehinkel, AWittchen, HUSchuster, P. Prevalence, 20-month incidence and outcome of unipolar depressive disorders in a community sample of adolescents. Psychological Med 1999;29:655–68.CrossRefGoogle Scholar
Dehmel, SWittchen, HU. Anmerkungen zur retrospektiven Erfassung von Lebensereignissen und Lebensbedingungen bei Verlaufsuntersuchungen – Bewertung und Vergessen -. Zeitschrift für Klinische Psychologie 1984;13:88–110.Google Scholar
StataCorp. Stata statistical software: Release 6.0. College Station, TX: Stata Corporation; 1999.Google Scholar
Royall, RM. Model robust confidence intervals using maximum likelihood estimators. Int Stat Rev 1986;54:221–6.CrossRefGoogle Scholar
Mathiesen, KSTambs, KDalgard, OS. The influence of social class, strain and social support on symptoms of anxiety and depression in mothers of toddlers. Social Psychiatry and Psychiatric Epidemiology 1999;34:61–72.CrossRefGoogle ScholarPubMed
Mazure, CMBruce, MLMaciejewski, PKJacobs, SC. Adverse life events and cognitive-personality characteristics in the prediction of major depression and antidepressant response. Am J Psychiatry 2000;157(6):896–903.Google ScholarPubMed
Prigerson, HGReynolds, CFFrank, EKupfer, DJGeorge, CJHouck, PR. Stressful life events, social rhythms, and depressive symptoms among the elderly. An examination of hypothesized causal linkages. Psychiatry Res 1994;51(1):33–49.CrossRefGoogle ScholarPubMed
Lewinsohn, PMRohde, PSeeley, JRKlein, DNGotlib, LH. Natural course of adolescent major depressive disorder in a community sample: predictors of recurrence in young adults. Am J Psychiatry 2000;157(10):1584–91.CrossRefGoogle Scholar
Wittchen, HUSchuster, PLieb, R. Comorbidity and mixed anxiety-depressive disorder: clinical curiosity or pathophysi-ological need? Human Psychopharmacol 2001;16:21–30.CrossRefGoogle ScholarPubMed
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