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The level of depressive, anxiety and obsessive-compulsive psychopathological dimensions in symptomatic versus asymptomatic SARS-CoV-2 infected pregnant women

Published online by Cambridge University Press:  01 September 2022

V.R. Enatescu ,
M. Dinescu ,
R. Kalinovic  and
G. Vlad
V.R. Enatescu*
Affiliation:
University of Medicine and Pharmacy “Victor Babes” Timisoara, Psychiatry, Timisoara, Romania
M. Dinescu
Affiliation:
“Pius Brinzeu” Emergency Clinical County Hospital Timisoara, “eduard Pamfil” Clinic Of Psychiatry, Timisoara, Romania
R. Kalinovic
Affiliation:
“Victor Babes” University of Medicine and Pharmacy, Biochemistry, TIMISOARA, Romania
G. Vlad
Affiliation:
“Pius Brinzeu” Emergency Clinical County Hospital Timisoara, “eduard Pamfil” Clinic Of Psychiatry, Timisoara, Romania
*
*Corresponding author.

Abstract

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Introduction

The neurotropic valence of SARS-CoV-2 has been revealed in several studies. Depressive and anxiety symptoms are more frequent in the perinatal period leading to maternal and neonatal negative outcomes. Accordingly, depressive and anxiety symptoms are more frequent in the perinatal period leading to negative consequences in both mothers and their neonates.

Objectives

To determine the level of depression, anxiety, and obsessive-compulsive symptoms depending on the severity of SARS-CoV-2 infection of pregnant women.

Methods

Based on the RT-PCR test, thirty-eight pregnant women with SARS-CoV-2 infection, hospitalized in Bega Clinic in Timisoara, were assessed concerning the presence of psychopathology. The severity of infection was dichotomized based on the presence or absence of the symptoms. The Edinburgh Postnatal Depression Scale, State and Trait Anxiety Inventory, and the Obsessive-Compulsive Inventory were administered to all participants.

Results

Of 38 recruited pregnant women, 12 (31,5%) had symptomatic SARS-CoV-2 infection. Symptomatic SARS-CoV-2 infected pregnant women had a higher average score of depression (p = 0.001) and state and trait anxiety (p = 0.002 and p < 0.001, respectively) compared to their asymptomatic counterparts. There were no differences in obsessive-compulsive symptoms (p > 0.05) in relation to the severity of SARS-CoV-2 infection.

Conclusions

The SARS-CoV-2 infection significantly interferes with the psychological status, thus jeopardizing the mental health of pregnant women. Therefore, SARS-CoV-2 infection should be considered an additional risk factor for anxiety and affective disorders during pregnancy.

Disclosure

No significant relationships.

Keywords

depressionanxietyobsessive-compulsiveSARS-CoV-2
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S537
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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