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Late Mania: Case Report

Published online by Cambridge University Press:  15 April 2020

M. Bel Feki
Affiliation:
Psychiatry, Razi Hospital, Tunis, Tunisia
S. Derouiche
Affiliation:
Psychiatry, Razi Hospital, Tunis, Tunisia
R. Kammoun
Affiliation:
Psychiatry, Razi Hospital, Tunis, Tunisia
O. Mziou
Affiliation:
Psychiatry, Razi Hospital, Tunis, Tunisia
L. Mnif
Affiliation:
Psychiatry, Razi Hospital, Tunis, Tunisia
W. Melki
Affiliation:
Psychiatry, Razi Hospital, Tunis, Tunisia

Abstract

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Introduction :

Bipolar disorders are frequent troubles touching 1 to 2% of the general population. The average age of disease onset is between 20 and 25 years. While the early onset is predictive of a more severe disorder, the late start, with elderly people, raises the problem of the frequency of secondary mania.

Methodology

Presentation of a clinical case and use of a bibliography from the following search engines: PubMed, Science direct, Medscape.

Case report

This case is about a 62-year-old woman, hypertensive and obese, who had a gastric by-pass complicated by deficiency neuropathy and Gayet Wernicke’s encephalopathy. While neurological symptoms were improved by treatment with B1 and B12 vitamins, carbamazepine and clomipramine, a state of psychomotor excitation persisted and prompted a psychiatric consultation. The diagnosis of a maniac episode was retained and the patient was put under mood stabilizer treatment.

Discussion

Etiological research discussed three cases:

A mania induced by Vitamin B12 deficiency, associated to neurological symptoms with impaired memory, paresthesia, and ataxia.

A mania induced by treatment with clomipramine.

A primary mania in an obese woman. This possibility is not uncommon. Indeed, several studies have confirmed the frequency of comorbidity of mood disorders and obesity.

Type
Article: 1463
Copyright
Copyright © European Psychiatric Association 2015
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