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Involuntary admission in psychiatric inpatient ward is related to antipsychotic polytherapy

Published online by Cambridge University Press:  16 April 2020

J. Ruiz
Affiliation:
Mental Health, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
E. Iniesta
Affiliation:
Mental Health, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
M. Portela
Affiliation:
Mental Health, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
K. Nieto
Affiliation:
Mental Health, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
P. Romero
Affiliation:
Mental Health, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
M.T. Tolosa
Affiliation:
Mental Health, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
I. Moreno
Affiliation:
Mental Health, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
M. Domato
Affiliation:
Mental Health, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
D. Fraguas
Affiliation:
Mental Health, Complejo Hospitalario Universitario de Albacete, Albacete, Spain Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain

Abstract

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Introduction

Involuntary admission of mentally ill patients tends to be related to clinical severity and worst therapeutic response.

Objectives

To evaluate whether there is a relationship between involuntary admission and prescription of two or more antipsychotics (that is, polytherapy) among patients with schizophrenia and other psychosis.

Methods

A total of 241 patients (40.2% females, mean age 39.7+/−13.0 years) consecutively admitted during 2009 to a psychiatric inpatient ward with diagnosis of schizophrenia and other psychoses were assessed.

Results

Out of the total sample, 150 (62.2%) patients were on polytherapy, and of the 241 patients 134 (55.6%) were involuntarily admitted. Involuntary admission was unrelated to age (p = 0.335), specific diagnosis (p = 0.452), or length of psychosis (p = 0.234). On the contrary, it was related to gender (61.8% of males vs. 46.4% of females were involuntary, p = 0.018) and to polytherapy/monotherapy prescription (62.0% of patients on polytherapy vs. 45.1% of patients on monotherapy were involuntarily admitted; and 53.3% of voluntary patients vs. 69.4% of involuntary were on polytherapy p = 0.010). After controlling for age, gender, specific diagnosis and length of psychosis the association between involuntary admission and being in polytherapy remained significant (p = 0.047).

Conclusions

Patients involuntarily admitted are more prone to be on antipsychotic polytherapy.

Type
P02-198
Copyright
Copyright © European Psychiatric Association 2011
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