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Implementation of a lifestyle and life-skills intervention to prevent weight-gain and cardiometabolic abnormalities in people with first-episode psychosis: the Keeping the Body in Mind program

Published online by Cambridge University Press:  01 September 2022

J. Curtis ,
S. Teasdale ,
R. Morell ,
P. Wadhwa ,
O. Lederman ,
H. Fibbins ,
A. Watkins  and
P. Ward
J. Curtis*
Affiliation:
South Eastern Sydney Local Health District, Keeping The Body In Mind Program, Bondi Junction, Australia UNSW Sydney & Mindgardens Neuroscience Network, School Of Psychiatry, Bondi Junction, Australia
S. Teasdale
Affiliation:
UNSW Sydney & Mindgardens Neuroscience Network, School Of Psychiatry, Bondi Junction, Australia
R. Morell
Affiliation:
UNSW Sydney & Mindgardens Neuroscience Network, School Of Psychiatry, Bondi Junction, Australia
P. Wadhwa
Affiliation:
UNSW Sydney & Mindgardens Neuroscience Network, School Of Psychiatry, Bondi Junction, Australia
O. Lederman
Affiliation:
South Eastern Sydney Local Health District, Keeping The Body In Mind Program, Bondi Junction, Australia
H. Fibbins
Affiliation:
South Eastern Sydney Local Health District, Keeping The Body In Mind Program, Bondi Junction, Australia
A. Watkins
Affiliation:
University of Sunshine Coast, Mind And Neuroscience - Thompson Institute, Birtinya, Australia
P. Ward
Affiliation:
UNSW Sydney & Mindgardens Neuroscience Network, School Of Psychiatry, Bondi Junction, Australia Ingham Institute for Applied Medical Research, Schizophrenia Research Unit, Liverpool, Australia
*
*Corresponding author.

Abstract

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Introduction

The development of obesity and metabolic abnormalities that seed future ill-health occur early with antipsychotic treatment. In 2013, the 12-week Keeping the Body in Mind (KBIM) pilot lifestyle intervention was delivered to a small sample of youth experiencing first-episode psychosis (FEP) with <4 weeks of antipsychotic exposure in a cluster-controlled design. The control group experienced significant increases in weight (mean 7.8kg) and waist circumference (mean 7.1cm) compared to non-significant increases (mean 1.8kg) in the KBIM group.

Objectives

To evaluate the effect of KBIM as routine care on anthropometry and metabolic biochemistry in a larger sample of youth with FEP across three mental health services.

Methods

This retrospective chart audit was conducted on youth with FEP, prescribed a therapeutic dose of antipsychotic medication, and who engaged with KBIM between 2015 and 2019. Primary outcomes were weight and waist circumference. Secondary outcomes were blood pressure, blood glucose and blood lipids. Outcomes were collected in a pre-post design. Implementation elements were also obtained from the participant’s medical file.

Results

One-hundred and eighty-two people met inclusion criteria. Follow-up data were available on up to 134 people for individual outcomes. Mean number of sessions attended was 11.1 (SD=7.3). Weight and waist changes were limited to 1.5kg (SD=5.3, t(133)=3.2, p=0.002) and 0.7cm (SD=5.8, t(109)=1.2, p=0.23). Nineteen percent experienced clinically significant weight gain. There were no changes to blood pressure or metabolic biochemistry.

Conclusions

The positive outcomes for weight and waist circumference found in the initial pilot study were maintained with implementation as routine care.

Disclosure

No significant relationships.

Keywords

First-episode psychosisAntipsychoticsweight-gainMetabolic
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S131 - S132
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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