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Familial factors influencing the consumption of anxiolytics and hypnotics by children and adolescents

Published online by Cambridge University Press:  16 April 2020

A. Pélissolo ,
D. Gourion ,
C. Notides ,
M. Bouvard ,
J.P. Lépine  and
M.C. Mouren-Siméoni
A. Pélissolo*
Affiliation:
Department of Psychiatry, Hôpital Fernand-Widal, AP-HP, 200 rue du Faubourg Saint-Denis, F75010Paris, France
D. Gourion
Affiliation:
Department of Psychiatry, Hôpital Fernand-Widal, AP-HP, 200 rue du Faubourg Saint-Denis, F75010Paris, France
C. Notides
Affiliation:
Department of Psychiatry, Hôpital Fernand-Widal, AP-HP, 200 rue du Faubourg Saint-Denis, F75010Paris, France
M. Bouvard
Affiliation:
Service Universitaire de psychiatrie Infanto-Juvénile, Centre Hospitalier Charles Perrens, 121 rue de la Béchade, 33076Bordeaux, France
J.P. Lépine
Affiliation:
Department of Psychiatry, Hôpital Fernand-Widal, AP-HP, 200 rue du Faubourg Saint-Denis, F75010Paris, France
M.C. Mouren-Siméoni
Affiliation:
Service de Psychopathologie de l’Enfant et de l’Adolescent, Hôpital Robert-Debré, AP-HP, 48 bd Serrurier, 75019Paris, France
*
*Correspondence and reprints: Department of psychiatry, Hôpital Pitié-Salpêtrière, 75651 Paris cedex. E-mail address: [email protected] (A. Pélissolo).
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Abstract

Many hypotheses have been made to explain the high rate of benzodiazepine consumption in France, including a general cultural and/or familial tendency to use certain types of psychotropic drugs. This study explored the association between lifetime medication use by parents and their children. Two hundred and twenty-one young patients (158 boys and 63 girls) consulting at a child and adolescent psychiatry department, six to 16 years of age (mean = 9.7 years), were screened for lifetime use of psychotropic drugs using a structured interview. Parents were asked about their own consumption, as well as their children’s. Lifetime consumption rates (at least once) were 22.2% in boys and 20.6% in girls, and 19.6% in children less than 11 years old. Higher rates were found in patients with emotional disorders (anxiety disorders and depression). In parents, 45.1% of mothers and 24.1% of fathers reported using medications at least once. A significant association was found between child and parental medication use: 34.1% of children had positive lifetime consumption when their mothers also used medications at least once versus only 13.6% in other children (odds ratio = 3.31 [1.68–6.50]; P = 0.001). The most significant association was found between medication use by girls and their mothers (odds ratio = 12.1 [2.38–61.5];P = 0.003). These data point to the existence of a family pattern of psychotropic drug consumption, especially in females.

Keywords

anxiolyticbenzodiazepinehypnoticpharmaco-epidemiology
Type
Original article
Information
European Psychiatry , Volume 16 , Issue 1 , February 2001 , pp. 11 - 17
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS.

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