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Exploring the link between character, personality disorder, and neuropsychological function

Published online by Cambridge University Press:  16 April 2020

Å.H Bergvall ,
T Nilsson  and
S Hansen
Å.H Bergvall
Affiliation:
Departments of Psychiatry (National Board of Forensic Medicine), and Psychology, Göteborg University, Box 500, Göteborg, 405 30, Sweden
T Nilsson
Affiliation:
Departments of Psychiatry (National Board of Forensic Medicine), and Psychology, Göteborg University, Box 500, Göteborg, 405 30, Sweden
S Hansen*
Affiliation:
Departments of Psychiatry (National Board of Forensic Medicine), and Psychology, Göteborg University, Box 500, Göteborg, 405 30, Sweden
*
*Corresponding author. Department of Psychology, Göteborg University, Box 500, Göteborg, SE 405 30, Sweden. E-mail address: [email protected] (S. Hansen).
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Abstract

Personality deviations and deficits in cognitive executive function are common among forensic populations. The present study on incarcerated offenders explored whether there are links between the two domains. Personality was assessed using the Temperament and Character Inventory (TCI). Neuropsychological performance, including visual working memory, attentional set-shifting and planning, were tested with the Cambridge Neuropsychological Test Automated Battery (CANTAB). Subjects with personality disorders scored high on harm avoidance, and low on self-directedness and cooperativeness. Personality disordered offenders did not differ from the comparison groups (offenders without personality disorder, and non-criminal controls) with regard to CANTAB measures of visual working memory (delayed matching to sample, spatial working memory) and planning (Stockings of Cambridge), but they made a larger number of errors on the attentional set-shifting task. Dimensional analysis of the personality and neuropsychological variables revealed significant associations between self-directedness and cooperativeness on the one hand, and attentional set-shifting on the other. Intellectually disabled, non-criminal individuals (marginal mental retardation) who performed poorly on attentional set-shifting also scored low on self-directedness and cooperativeness. The results indicate that poor development of certain personality traits may be associated with deficits in neuropsychological functioning.

Keywords

Attentional set-shiftingCambridge Neuropsychological Test Automated Battery (CANTAB)Executive functionsPersonality disorderTemperament and Character Inventory (TCI)Marginal mental retardation
Type
Original article
Information
European Psychiatry , Volume 18 , Issue 7 , November 2003 , pp. 334 - 344
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS.

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References

Anderson, SWBechara, ADamasio, HTranel, DDamasio, AR. Impairment of social and moral behavior related to early damage in human prefrontal cortex. Nature Neurosci 1999;2:1032–7.CrossRefGoogle ScholarPubMed
Bergvall Å, HWessely, HForsman, AHansen, S. A deficit in attentional set-shifting of violent offenders. Psychol Med 2001;31:1095–105.CrossRefGoogle ScholarPubMed
Best, MWilliams, JMCoccaro, EF. Evidence for a dysfunctional prefrontal circuit in patients with an impulsive aggressive disorder. Proc Nat Acad Sci USA 2002;99:8448–53.CrossRefGoogle ScholarPubMed
Blackburn, R. Replicated personality disorder clusters among mentally disordered offenders and their relation to dimensions of personality. J Pers Disorders 1996;10:68–81.CrossRefGoogle Scholar
Brändström, SSchlette, PPrzybeck, TRLundberg, MSigvardsson, SNylander, P-O, et al. Swedish normative data on personality using the Temperament and Character Inventory (TCI). Compr Psych 1998;39:122–8.CrossRefGoogle Scholar
Brown, VLBowman, EM. Rodent models of prefrontal cortical function. Trends Neurosci 2002;25:340–3.CrossRefGoogle ScholarPubMed
Caspi, A. The child is the father of the man: personality continuities from childhood to adulthood. J Pers Soc Psychol 2000;78:158–72.CrossRefGoogle ScholarPubMed
Caspi, AElder, GHBem, DJ. Moving against the world: life-course patterns of explosive children. Dev Psych 1987;23:308–13.CrossRefGoogle Scholar
Caspi, AMoffitt, TESilva, PAStouthamer-Loeber, MKrueger, RFSchmutte, PS. Are some people crime-prone? Replications of the personality-crime relationship across countries, genders, races, and methods. Criminology 1994;32:163–95.CrossRefGoogle Scholar
Clark, LGoodwin, GMIversen, SD. Frontal lobe function in the euthymic phase of bipolar disorder. Soc Neurosci Abstr 1999;25:839.10.Google Scholar
Cloninger, CRSvrakic, DMPrzybeck, TR. A psychobiological model of temperament and character. Arch Gen Psychiatry 1993;50:975–90.CrossRefGoogle ScholarPubMed
Cloninger, CRPrzybeck, TRSvrakic, DNWetzel, RD. The temperament and character inventory (TCI): a guide to its development and use. St. Louis: Washington University; 1994.Google Scholar
Cloninger, CRSigvardsson, SBohman, M. Childhood personality predicts alcohol abuse in young adults. Alcohol Clin Exp Res 1988;12:494–505.CrossRefGoogle ScholarPubMed
Cohen, JCohen, P. Applied multivariate regression/correlation analysis for the behavioral sciences. 2nd ed. Hillsdale (NJ): Erlbaum; 1983.Google Scholar
Colacicco, GWelzl, HLipp, H-PWürbel, H. Attentional set-shifting in mice: modification of a rat paradigm, and evidence for strain-dependent variation. Behav Brain Res 2002;13:95–102.CrossRefGoogle Scholar
Damasio, ARTranel, DDamasio, H. Individuals with sociopathic behavior caused by frontal damage fail to respond automatically to social stimuli. Behav Brain Res 1990;41:81–94.CrossRefGoogle Scholar
Devonshire, PAHoward, RCSellars, C. Frontal lobe functions and personality in mentally abnormal offenders. Pers Individ Diff 1988;9:339–44.CrossRefGoogle Scholar
Dias, RRobbins, TWRoberts, AC. Dissociation in prefrontal cortex of affective and attentional shifts. Nature 1996;380:68–72.CrossRefGoogle ScholarPubMed
Dias, RRobbins, TWRoberts, AC. Dissociable forms of inhibitory control within prefrontal cortex with an analog of the Wisconsin Card Sort Test: restriction to novel situations and independence from ‘on-line’ processing. J Neurosci 1997;17:9285–97.CrossRefGoogle ScholarPubMed
Dimitrov, MPhipps, MZahn, TPGrafman, J. A thoroughly modern Gage. Neurocase 1999;5:345–54.CrossRefGoogle Scholar
Dinn, WMHarris, CL. Neurocognitive function in antisocial personality disorder. Psychiatry Res 2000;97:173–90.CrossRefGoogle ScholarPubMed
Dolan, MPark, I. The neuropsychology of antisocial personality disorder. Psychol Med 2002;32:417–27.CrossRefGoogle ScholarPubMed
Eriksson, LJohansson, EKettaneh-Wold, NWold, S. Multi- and mega-variate data analysis. Principles and applications. Umeå: Umetrics Academy; 2001.Google Scholar
Eslinger, PJ. Neurological and neuropsychological bases of empathy. Eur Neurol 1998;39:193–9.CrossRefGoogle ScholarPubMed
Eslinger, PJDamasio, AR. Severe disturbance of higher cognition after bilateral frontal lobe ablation: patient EVR. Neurology 1985;35:1731–41.CrossRefGoogle ScholarPubMed
Evenden, JL. Varieties of impulsivity. Psychopharmacology 1999;146:348–61.CrossRefGoogle ScholarPubMed
Farrow, DZheng, YWilkinson, IDSpence, SADeakin, JFWTarrier, N, et al. Investigating the functional anatomy of empathy and forgiveness. NeuroReport 2001;12:2433–8.CrossRefGoogle ScholarPubMed
Fray, PJRobbins, TWSahakian, BJ. Neuropsychiatric applications of CANTAB. Int J Geriat Psych 1996;11:329–36.3.0.CO;2-6>CrossRefGoogle Scholar
Gorenstein, EE. Frontal lobe functions in psychopaths. J Abnormal Psychol 1982;91:368–79.CrossRefGoogle ScholarPubMed
Grattan, LMEslinger, PJ. Long-term psychological consequences of childhood frontal lobe lesion in patient DT. Brain Cogn 1992;20:185–95.CrossRefGoogle ScholarPubMed
Hansson, LOWaters, NWinblad, BGottfries, C-GCarlsson, A. Evidence for biochemical heterogeneity in schizophrenia: a multivariate study of monoaminergic indices in human post-mortal tissue. J Neural Trans 1994;98:217–35.CrossRefGoogle ScholarPubMed
Henningsson, MSundbom, EArmelius, B-ÅErdberg, P. PLS model building: a multivariate approach to personality data. Scand J Psychol 2001;42:399–409.CrossRefGoogle Scholar
Hughes, CRussell, JRobbins, TW. Evidence for executive dysfunction in autism. Neuropsychologia 1994;32:477–92.CrossRefGoogle ScholarPubMed
Jacobs, GDSnyder, D. Frontal brain asymmetry predicts affective style in men. Behav Neurosci 1996;110:3–6.CrossRefGoogle ScholarPubMed
Johnson, JGCohen, PCSmailes, EKasen, SOldham, JMSkodol, E, et al. Adolescent personality disorders associated with violence and criminal behavior during adolescence and early adulthood. Am J Psychiatry 2000;157:1406–12.CrossRefGoogle ScholarPubMed
Kandel, EFreed, D. Frontal-lobe dysfunction and antisocial behavior: a review. J Clin Psychol 1989;45:404–13.3.0.CO;2-G>CrossRefGoogle ScholarPubMed
Kempton, SVance, AMaruff, PLuk, ECostin, JPantelis, C. Executive function and attention deficit hyperactivity disorder: stimulant medication and better executive function performance in children. Psychol Med 1999;2:527–38.CrossRefGoogle Scholar
af Klinteberg, B. The psychopathic personality in a longitudinal perspective. Eur Child Adolesc Psychiatry 1996;5:57–63.CrossRefGoogle Scholar
af Klinteberg, B. Biology, norms, and personality: a developmental perspective. Neuropsychobiol 1996;34:146–54.CrossRefGoogle ScholarPubMed
af Klinteberg, BHallman, JOreland, LWirsén, ALevander, SESchalling, D. Exploring the connections between platelet monoamine oxidase activity and behavior II. Impulsive personality without neuropsychological signs of disinhibition in air force pilot recruits. Neuropsychobiology 1992;26:136–45.CrossRefGoogle ScholarPubMed
Krueger, RFSchmutte, PSCaspi, AMoffitt, TECampbell, KSilva, PA. Personality traits are linked to crime among men and women: evidence from a birth cohort. J Abnorm Psychology 1994;103:328–38.CrossRefGoogle ScholarPubMed
Lahey, BBWaldman, IDMcBurnett, K. Annotation: the development of antisocial behavior: an integrative causal model. J Child Psychol Psychiat 1999;40:669–982.CrossRefGoogle Scholar
Lapierre, DBraun, CMJHodgins, S. Ventral frontal deficits in psychopathy: neuropsychological test findings. Neuropsychologia 1995;33:139–51.CrossRefGoogle ScholarPubMed
Luciana, MNelson, CA. The functional emergence of prefrontally-guided working memory systems in four- to eight-year-old children. Neuropsychologia 1998;36:273–93.CrossRefGoogle ScholarPubMed
Malmgren-Olsson, E-BArmelius, B-Å. Physical and psychological health and social relations in patients with prolonged musculoskeletal disorders. Nordic College Caring Sci 2001;15:181–9.Google ScholarPubMed
Miller, EK. The prefrontal cortex and cognitive control. Nature Rev Neuroscience 2000;1:59–65.CrossRefGoogle ScholarPubMed
Moffitt, TE. Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. Psychol Rev 1993;100:674–701.CrossRefGoogle ScholarPubMed
Morgan, ABLilienfeld, SO. A meta-analytic review of the relation between antisocial behavior and neurpsychological measures of executive function. Clin Psychol Rev 2000;20:113–36.CrossRefGoogle Scholar
Mulder, RTJoyce, PRSullivan, PFBulik, CMCarter, FA. The relationship among three models of personality psychopathology: DSM-III-R personality disorder, TCI scores and DSQ defences. Psychol Med 1999;2:943–51.CrossRefGoogle Scholar
Nilsson, MWaters, SWaters, NCarlsson, ACarlsson, ML. A behavioural pattern analysis of hypoglutamatergic mice—effects of four different antipsychotic agents. J Neural Transm 2001;10:1181–96.CrossRefGoogle Scholar
Ornstein, TJIddon, JLBaldacchino, AMSahakian, BJLondon, MEveritt, BJ, et al. Profiles of cognitive dysfunction in chronic amphetamine and heroin abusers. Neuropsychopharmacology 2000;23:113–26.CrossRefGoogle ScholarPubMed
Owen, AMRoberts, ACHodges, RSummers, BAPolkey, CERobbins, TW. Contrasting mechanisms of impaired attentional set-shifting in patients with frontal lobe damage or Parkinson’s disease. Brain 1993;116:1159–79.CrossRefGoogle ScholarPubMed
Pantelis, CBarnes, TRENelson, HETanner, SWeatherley, LOwen, AM, et al. Frontal-striatal cognitive deficits in patients with chronic schizophrenia. Brain 1997;120:1823–43.CrossRefGoogle ScholarPubMed
Patterson, CMNewman, JP. Reflectivity and learning from aversive events: toward a psychological mechanism for the syndromes of disinhibition. Psychol Rev 1999;100:716–36.CrossRefGoogle Scholar
Pliszka, SRLiotti, MWoldorff, MG. Inhibitory control in children with attention-deficit/hyperactivity disorder: event-related potentials identify the processing component and timing of an impaired right-frontal response-inhibition mechanism. Biol Psychiatry 2000;48:238–46.CrossRefGoogle ScholarPubMed
Price, BHDaffner, KRStowe, RMMesulam, MM. The compartmental learning disabilities of early frontal lobe damage. Brain 1990;113:1383–93.CrossRefGoogle Scholar
Purcell, RMaruff, PKyrios, MPantelis, C. Neuropsychological function in young patients with unipolar major depression. Psychol Med 1997;27:1277–85.CrossRefGoogle ScholarPubMed
Rahman, SSahakian, BJHodges, JRRogers, RDRobbins, TW. Specific cognitive deficits in mild frontal variant frontotemporal dementia. Brain 1999;122:1469–93.CrossRefGoogle ScholarPubMed
Raine, A. Annotation: the role of prefrontal deficits, low autonomic arousal, and early health factors in the development of antisocial and aggressive behavior in children. J Child Psychol Psychiatry 2002;43:417–34.CrossRefGoogle ScholarPubMed
Raine, ALencz, TBihrle, SLa Casse, LColletti, P. Reduced prefrontal gray matter volume and reduced autonomic activity in antisocial personality disorder. Arch Gen Psychiatry 2000;57:119–27.CrossRefGoogle ScholarPubMed
Rasmussen, KStorsaeter, OLevander, S. Personality disorders, psychopathy, and crime in a Norwegian prison population. Int J Law Psychiatry 1999;22:91–7.CrossRefGoogle Scholar
Robbins, TW. Dissociating executive functions of the prefrontal cortex Phil Trans Royal Soc Lond series B 1996;351:1463–71.Google ScholarPubMed
Roberts, ACRobbins, TWWeiskrantz, L, editors. Executive and cognitive functions of the prefrontal cortex. Phil Trans Royal Soc Lond Series B, 351. 1996. p. 1387–527.Google Scholar
Rogers, RDAndrews, TCGrasby, PMBrooks, DJRobbins, TW. Contrasting cortical and subcortical activations produced by attentional-set-shifting and reversal learning in humans. J Cogn Neurosci 2000;12:142–62.CrossRefGoogle ScholarPubMed
Schalling, DRosén, A-S. Porteus maze differences between psychopathic and non-psychopathic criminals. Br J Soc Clin Psychol 1968;7:224–8.CrossRefGoogle Scholar
Silverthorn, PFrick, PJ. Developmental pathways to antisocial behavior: the delayed-onset pathway in girls. Dev Psychopathol 1999;11:126–91.CrossRefGoogle ScholarPubMed
Smith, EEJonides, J. Storage and executive processes in the frontal lobes. Science 1999;283:1657–61.CrossRefGoogle ScholarPubMed
Söderström, H. Neuropsychiatric background factors to violent crime Ph.D. Thesis, Göteborg University ISBN 91-628-5243-4. 2002.Google Scholar
Stuss, DTGow, CAHetherington, CR. ‘No longer Gage’: frontal lobe dysfunction and emotional changes. J Consult Clin Psychol 1992;60:349–59.CrossRefGoogle Scholar
Stuss, DTLevine, B. Adult clinical neuropsychology: lessons from studies of the frontal lobes. Ann Rev Psychol 2002;53:401–33.CrossRefGoogle ScholarPubMed
Svrakic, DMWhitehead, CPrzybeck, TRCloninger, CR. Differential diagnosis of personality disorders by the seven factor model of temperament and character. Arch Gen Psychiatry 1993;50:991–9.CrossRefGoogle ScholarPubMed
van Honk, JHermans, EJPutman, PMontagne, BSchutter, DJLG. Defective somatic markers in sub-clinical psychopathy. NeuroReport 2002;13:1025–7.CrossRefGoogle ScholarPubMed
Vold, GBBernard, TJSnipes, JB. Theoretical criminology. New York: Oxford University Press; 1998.Google Scholar
Wheeler, REDavidson, RJTomarken, AJ. Frontal brain asymmetry and emotional reactivity: a biological substrate of affective style. Psychophysiology 1993;30:82–9.CrossRefGoogle ScholarPubMed
White, JLMoffitt, TECaspi, ABartusch, DJNeedles, DJStouthamer-Loeber, M. Measuring impulsivity and examining its relationship to delinquency. J Abnorm Psychol 1994;103:192–205.CrossRefGoogle ScholarPubMed
Williams, DMateer, CA. Developmental impact of frontal lobe injury in middle childhood. Brain Cogn 1992;20:196–204.CrossRefGoogle ScholarPubMed
Wold, SSjöström, M. Chemometrics, present and future success. Chemometrics Intelligent Lab Syst 1998;44:3–14.CrossRefGoogle Scholar
Yeudall, LTFromm-Auch, D. Neuropsychological impairments in various psychopathological populations. In: Gruzelier, JFlor-Henry, P, editors.Hemisphere asymmetries of function in psychopathology. Amsterdam: Elsevier/North-Holland Biomedical Press; 1979. p. 401–28.Google Scholar
Zald, DHMattsson, DHPardo, JV. Brain activity in ventromedial prefrontal cortex correlates with individual differences in negative affect. Proc Nat Acad Sci USA 2002;99:2450.CrossRefGoogle ScholarPubMed
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