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EPA-1235 – Basic Symptoms, Stress and Executive Functions in Patients Readmitted to Acute Psychiatric Wards: Preliminary Results From an Observational Study

Published online by Cambridge University Press:  15 April 2020

G. Parmigiani ,
G. Mandarelli ,
L. Tarsitani ,
V. Roselli ,
D. Di Cosimo ,
F. Moscati ,
E. Fabi ,
I. Gaviano ,
A. Buscajoni  and
T. Scattolin
...Show all authors
G. Parmigiani
Affiliation:
Neurology and Psychiatry, Sapienza University of Rome Policlinico Umberto I Hospital, Rome, Italy
G. Mandarelli
Affiliation:
Neurosciences Mental Health and Sensory Organs, Sapienza University of Rome Sant’ Andrea Hospital, Rome, Italy
L. Tarsitani
Affiliation:
Neurology and Psychiatry, Sapienza University of Rome Policlinico Umberto I Hospital, Rome, Italy
V. Roselli
Affiliation:
Neurology and Psychiatry, Sapienza University of Rome Policlinico Umberto I Hospital, Rome, Italy
D. Di Cosimo
Affiliation:
Neurosciences Mental Health and Sensory Organs, Sapienza University of Rome Sant’ Andrea Hospital, Rome, Italy
F. Moscati
Affiliation:
Neurosciences Mental Health and Sensory Organs, Sapienza University of Rome Sant’ Andrea Hospital, Rome, Italy
E. Fabi
Affiliation:
Neurology and Psychiatry, Sapienza University of Rome Policlinico Umberto I Hospital, Rome, Italy
I. Gaviano
Affiliation:
Neurology and Psychiatry, Sapienza University of Rome Policlinico Umberto I Hospital, Rome, Italy
A. Buscajoni
Affiliation:
Neurosciences Mental Health and Sensory Organs, Sapienza University of Rome Sant’ Andrea Hospital, Rome, Italy
T. Scattolin
Affiliation:
Neurosciences Mental Health and Sensory Organs, Sapienza University of Rome Sant’ Andrea Hospital, Rome, Italy
M. Biondi
Affiliation:
Neurology and Psychiatry, Sapienza University of Rome Policlinico Umberto I Hospital, Rome, Italy
S. Ferracuti
Affiliation:
Neurosciences Mental Health and Sensory Organs, Sapienza University of Rome Sant’ Andrea Hospital, Rome, Italy

Abstract

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Introduction:

The vulnerability-stress model assumes that psychotic symptoms emerge from the interaction between stress, basic symptoms and information processing deficits. Despite the large amount of data on first episode psychosis, this particular topic has been investigated to a minor extent in patients readmitted to acute psychiatric wards.

Objectives:

To assess the association between basic symptoms and subjective stress, life events, and executive functions.

Aims:

To identify the factors associated to basic symptoms during relapses.

Methods:

Patients affected by schizophrenia, schizoaffective and bipolar disorder according to DSM-IV TR were recruited from the acute psychiatric wards of two University Hospitals in Rome. They were evaluated through: a) Frankfurt Complaint Questionnaire (FCQ); b) Stress-related Vulnerability Scale (SVS); c) Paykel Interview for Recent Life Events (IRLE); d) Wisconsin Card Sorting Test (WCST).

Results:

Forty-nine patients were enrolled (65% women; mean age 42.7 ± 10.5 years; education 12.4 ± 3.2 years; disease duration 17.6 ± 11.4; 63% affected by bipolar disorder). Basic symptoms were positively associated to SVS total score (rho = 0.66, p < 0.01), IRLE marital subscale (rho = 0.3, p < 0.05), while negatively associated to WCST number of completed categories (rho = −0.32, p < 0.05).

Conclusions:

Preliminary results of this study show that basic symptoms are positively associated to perceived stress and marital life events, while negatively associated to executive functions, during psychotic relapses.

Type
P26 - Psychopathology
Information
European Psychiatry , Volume 29 , Issue S1: Abstracts of the 22nd European Congress of Psychiatry , 2014 , pp. 1
Copyright
Copyright © European Psychiatric Association 2014
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