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EPA-0481 – The Evaluation of Night Eating Syndrome Treatment

Published online by Cambridge University Press:  15 April 2020

I. Makhortova
Affiliation:
Psychiatry, LLC “LION-MED”, Voronezh, Russia
B. Tsygankov
Affiliation:
Psychiatry Narcology and Psychotherapy, Moscow State Medical Stomatological University A.I. Evdokimova, Moscow, Russia
O. Shiryaev
Affiliation:
Psychiatry and Narcology, Voronezh State Medical Academy, Voronezh, Russia

Abstract

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The objective of this investigation was to evaluate the efficacy of night eating syndrome (NES) treatment. A randomized sample of patients (n=96) age 31-65 years was observed. All patients had NES according to the diagnostic criteria. The level of NES was evaluated using Night Eating Questionnaire (NEQ). The sample was divided in two groups according to clinical characteristics of NES. ‘Evening eating’ (n=57) group had more episodes of taking food after dinner, but before going to sleep. They usually didn’t have episodes of eating during night. The ‘night eating’ group (n=39) had more episodes of night eating after going to sleep, and didn’t usually eat after dinner. Both groups were randomly divided into two treatment groups: first group was prescribed Sertraline (50-100 mg per day), second group was prescribed Agomelatine (25-50 mg per day). The sample was observed on before treatment (D0) and after 2 months (D60). Results are presented in the table<

/p>Dynamics of NEQ score in groups

EveningNight
SertralineAgomelatineSertralineAgomelatine
Patients29281819
NEQ_D033,97±0,9532,80±0,8038,33±0,89*37,68±1,44*
NEQ_D6022,28±1,08*27,00±1,75*30,61±1,09*23,16±1,32*
*

- p<0,05

As seen in the table, the overall score of NEQ was significantly higher (p<0,05) in the ‘night’ group. Also that the NEQ score of patients with ‘evening eating’, who took Sertraline is lower (p<0,05) than in those, who received Agomelatine. In patients, who had ‘night eating’: those who took Agomelatine appear to have lower scores (p<0,05).

It is possible to conclude that prescribing Sertraline is more effective in patients with mostly ‘evening eating’ and prescribing Agomelatine – in those with ‘night eating’.

Type
EPW42 - Eating Disorders
Copyright
Copyright © European Psychiatric Association 2014
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