The frailty of elderly in Tenth Decade with stroke was considered a certainty for many years ruling, and the stroke in 90 year old was a paradigm of fragility in gerontology. However soon enough the existing data on the population in nursing homes.

The aim of this study was to evaluate the response to therapy SSRI antidepressants (fluoxetine 20–40 mg; sertraline 25–100 mg,; citalopram 10–40 mg) in a population of olds with depression after-stroke hospitalized in Nursing Home (RSA) at Catania (Sicily). We evaluated a total sample of 66 patients comparing the 13 patients 90yr-old with the 53 patients younger pertaining to the same RSA for stroke.

Stackable with somatic comorbidity and the post-stroke depression between the two populations, we founded:

1. 1. Both populations are responsive to antidepressant treatment with SSRIs

2. 2. The ninety recover more and more 'rapid cognitive impairment

3. 3. Both Populations improves the performances with rehabilitation recovering functional self-autonomy, albeit from different levels.

4. 4. The nutrient levels overlap in both populations and increased fragility biological of over 90-year old is evident for among of Prevalence and incidence of Delirium and Presence of Pressure Sores.

According to this data the response to antidepressants seems to be good and totally overlapped with the population most 'young studied as a reference.

This data also confirms that it is not age itself but the comorbidity of diseases present that make it’ a frail old man and that probably the frailty of the nineties is a biological myth.