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Efficacy of lithium treatment in Kleine–Levin syndrome

Published online by Cambridge University Press:  16 April 2020

F. Muratori ,
N. Bertini  and
G. Masi
F. Muratori*
Affiliation:
Division of Child Neurology and Psychiatry, University of Pisa (Italy), IRCCS Stella Maris, Via dei Giacinti 2, 56018 Calambrone (Pi), Pisa, Italy
N. Bertini
Affiliation:
Division of Child Neurology and Psychiatry, University of Pisa (Italy), IRCCS Stella Maris, Via dei Giacinti 2, 56018 Calambrone (Pi), Pisa, Italy
G. Masi
Affiliation:
Division of Child Neurology and Psychiatry, University of Pisa (Italy), IRCCS Stella Maris, Via dei Giacinti 2, 56018 Calambrone (Pi), Pisa, Italy
*
*Corresponding author. E-mail address: [email protected] (F. Muratori).
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Summary

The Kleine–Levin syndrome (KLS) is characterized by periodic, sudden-onset episodes of hypersomnia, compulsive hyperphagia, and behavioral–emotional symptoms, lasting from a few days to a few weeks, with complete remission in the intercritical periods. We report on efficacy of lithium treatment in a highly recurring form of the disorder in a 17-year-old male adolescent. The decreasing severity of the disorder paralleled the progressive increase of lithium dosage, up to 0.9 mEq l–1. Implications regarding the pharmacological treatment of this neglected disorder are discussed.

Keywords

Kleine-Levin syndromeLithiumAdolescence
Type
Case Reports
Information
European Psychiatry , Volume 17 , Issue 4 , July 2002 , pp. 232 - 233
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2002

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References

Billiard, MCadhilac, JLes hypersomnies recurrentes. Rev Neurol 1988;144:249–58.Google Scholar
Gillberg, CKleine–Levin Syndrome: unrecognized diagnosis in adolescent psychiatry. J Am Acad Child Adolesc Psychiatry 1987;26(5):793–4.CrossRefGoogle ScholarPubMed
Goldberg, MAThe treatment of Kleine–Levin syndrome with lithium. Can J Psychiatry 1988;28:491–3.CrossRefGoogle Scholar
Lemire, IRevue de syndrome de Kleine–Levin: vers une approche intégrée. Can J Psychiatry 1993;38:277–84.CrossRefGoogle Scholar
McIntyree, RSet al.Lithium revisited. Can J Psychiatry 2001; 46:322–7.CrossRefGoogle Scholar
Masi, GFavilla, LMucci, MThe Kleine–Levin syndrome as a neuropsychiatric disorder: a case report. Psychiatry 2000;63: 93–100.CrossRefGoogle ScholarPubMed
Mukaddes, NMet al.Carbamazepine for Kleine–Levin Syndrome. Letter to editor. J Am Acad Child Adolesc Psychiatry 1999;38(7):791–2.CrossRefGoogle Scholar
Orlosky, MJThe Kleine–Levin syndrome: a review. Psychosomatics 1982;23:6609–21.CrossRefGoogle ScholarPubMed
Sagar, RSKhandelwal, SKGupta, SInterepisodic morbidity in Kleine–Levin syndrome. Br J Psychiatry 1990;157:139–41.CrossRefGoogle ScholarPubMed
Douglas, NJWhy am I sleepy. Am J Resp Crit Care Med 2001;163:1310–3.CrossRefGoogle Scholar
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