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Dynamic Correction of the Activity Sympathetic Nervous System (Dcasns) to Restore Cognitive Functions

Published online by Cambridge University Press:  15 April 2020

T.S. Petrenko ,
V.S. Kublanov  and
K.Y. Retiunskiy
T.S. Petrenko
Affiliation:
Psychiatry, Ural Sate Medical University, Yekaterinburg, Russia
V.S. Kublanov
Affiliation:
Institute of radioelectronics and information technology, Ural Federal University, Yekaterinburg, Russia
K.Y. Retiunskiy
Affiliation:
Psychiatry, Ural State Medical University, Yekaterinburg, Russia

Abstract

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Introduction

The efficiency DCASNS method to restore cognitive function in patients with organic amnestic syndrome.

Objectives

Three patients with clinical organic amnestic syndrome resulting of brain damage (poisoning, alcohol and trauma) held inpatient treatment for at least 12 months in the neurology or psychiatry department without a significantly improvement.

Aims

Determine of the effectiveness of the DCASNS method to restore cognitive functions.

Methods

DCASNS method implemented using an electrical pulse generator that delivers the spatially-distributed field of the carefully-controlled current pulses in the nervous structures of the neck (Kublanov V.S., 2008). This allow to control of autonomic regulation activity (by stellatis ganglion) and stimulate stem neural centers. Patients were assessed using the clinical method, neuropsychological scales: Frontal Assessment Batter? (FAB), Montreal Cognitive Assessmnet (MCA), Mini-Mental State (MMSE), MRI, EEG, Heart rate variability (HRV).

Results

The initial clinical state of the patients was severe, with structural damage on MRI and low rates of neuropsychological tests. As a result of seven DCASNS procedures improved significantly neuropsychological assessments: FAB (from 5,7±3,1 to 12±4,0); MCA (from 11,3±3,0 to 16,3±4,0); MMSE (from 15,3±6,2 to 21,3±8,3). EEG comparison analysis showed an increase in power of Alpha waves and power reduction of Delta waves on all leads. HRV comparison analysis showed an increase total power and the change in autonomic balance.

Conclusion

DCASNS method can be used for the effectiveness treatment of cognitive dysfunctions resulting organic lesions of the central nervous system.

Type
Article: 0843
Information
European Psychiatry , Volume 30 , Issue S1: Abstracts of the 23rd European Congress of Psychiatry , March 2015 , pp. 1
Copyright
Copyright © European Psychiatric Association 2015
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