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A Dimensional Redefinition of the Schizophrenia Spectrum: Delusional Disorder Versus Schizophrenia Versus Schizoaffective Disorder

Published online by Cambridge University Press:  15 April 2020

J.E. Muñoz Negro ,
I. Ibáñez-Casas ,
E. De Portugal  and
J. Cervilla Ballesteros
J.E. Muñoz Negro
Affiliation:
1.Mental Health Management Clinical Unit Hospital Universitario San Cecilio. 2.Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), 1. Andalusian Health Service. 2. University of Granada., Granada, Spain
I. Ibáñez-Casas
Affiliation:
Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), University of Granada., Granada, Spain
E. De Portugal
Affiliation:
Department of Psychiatry Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Hospital General Universitario Gregorio Marañón ., Madrid, Spain
J. Cervilla Ballesteros
Affiliation:
1. Mental Health Management Clinical Unit Hospital Universitario San Cecilio. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), 1. Andalusian Health Service.2. University of Granada., Granada, Spain

Abstract

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Introduction

Since the early description of paranoia, nosology of delusional disorder has always been controversial. The idea of ??unitary psychosis is old but has now taken on new value from the dimensional continuum model of psychosis.

Aims

1. To study the psychopathological dimensions of the schizophrenia spectrum. 2. To explore the relationship between the dimensions obtained and the categorical diagnoses. 3 To compare the different diagnoses of the psychosis from a psychopathological and functional point of view.

Material and Methods

an observational study with 550 patients was conducted. 373 patients with schizophrenia, 137 patients with delusional disorder, 40 patients with schizoaffective disorder. PANSS was used to assess the psychopathology and GAF for global functioning. Exploratory and confirmatory factor analysis of the PANSS items was performed in order to obtain a dimensional model. The relationship between diagnostic categories and dimensions was subsequently studied with ANOVA tests.

Results

5 Factors,-manic, negative symptoms, depression, positive symptoms and cognition-, similar in composition to other models were obtained. The model yielded the 57.27% of the total variance. The dimensional model obtained was able to explain the differences and similarities between the different categories of the schizophrenia spectrum and the validity of the categories was questioned. The value of the model in order to help establish the diagnosis, prognosis and treatment decision-making was postulated.

Keywords

delusional disorderDSM-5Factor analysisdimensionalpsychosis continuum
Type
Article: 0898
Information
European Psychiatry , Volume 30 , Issue S1: Abstracts of the 23rd European Congress of Psychiatry , March 2015 , pp. 1
Copyright
Copyright © European Psychiatric Association 2015
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