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Development and validation of polish version of matrics consensus cognitive battery

Published online by Cambridge University Press:  16 April 2020

A. Ciołkiewicz ,
M. Jędrasik ,
M. Denisiuk ,
M. Linke ,
A. Gruszka ,
I. Zdunek ,
M. Jarema  and
A. Wichniak
A. Ciołkiewicz
Affiliation:
Third Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland
M. Jędrasik
Affiliation:
Third Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland
M. Denisiuk
Affiliation:
Third Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland
M. Linke
Affiliation:
Third Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland
A. Gruszka
Affiliation:
Third Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland
I. Zdunek
Affiliation:
Third Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland
M. Jarema
Affiliation:
Third Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland
A. Wichniak
Affiliation:
Third Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland

Abstract

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Introduction

Neurocognitive deficits account for most of the long-term poor functional outcomes of patients with schizophrenia. Effective treatment of cognitive impairment is the most important challenge in the treatment of this disorder.

Objectives

Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Project produced a battery of 10 tests called the MATRICS Consensus Cognitive Battery (MCCB), designed to asses cognitive treatment effects in clinical trials of patients with schizophrenia.

Methods

In this validation study of Polish version of MCCB, 120 patients with schizophrenia will be investigated. 60 of them will be randomly chosen and examined again after 4 week. Altogether MCCB is going to be applied 180 times on 120 patients. The results will be compared with the results of American standardization study of MCCB (MATRICS-PASS).

Results

Until now 19 patients (12 males, 7 females, mean age 25.63 ± 5.14) have been investigated. Following MCCB T-scores in seven cognitive domains were obtained: attention/vigilance (38.33 ± 9.03), working memory (40.95 ± 14.35), verbal learning (38.11 ± 8.37), visual learning (41.37 ± 10.48), reasoning/problem solving (36.95 ± 10.14), social cognition (35.79 ± 10.67), composite T-score (30.22 ± 12.93).

Conclusions

These preliminary results show that MCCB could be successfully adopted into Polish. After the end of validation process MCCB will be an important research tool in studies aiming at improvement of cognitive functioning in Polish patients with schizophrenia.

Type
P03-192
Information
European Psychiatry , Volume 26 , Issue S2: Abstracts of the 19th European Congress of Psychiatry , March 2011 , pp. 1361
Copyright
Copyright © European Psychiatric Association 2011
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