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Depression and quality of life in hospitalised patients with congestive heart failure (CHF): A cross-sectional study from Karachi, Pakistan

Published online by Cambridge University Press:  23 March 2020

M. Husain*
Affiliation:
Institute of psychiatry - psychology and neuroscience, centre for affective disorders, London, United Kingdom
K. Tayyeba
Affiliation:
University of Manchester, brain- behaviour and mental health, Manchester, United Kingdom
M. Husain
Affiliation:
South London and Maudsley NHS Foundation Trust, Liaison Psychiatry King's college hospital, London, United Kingdom
B. Fatima
Affiliation:
Pakistan institute of learning and living, mental health, Karachi, Pakistan
S.U.H. Ansari
Affiliation:
Pakistan institute of learning and living, mental health, Karachi, Pakistan
R. Rahman
Affiliation:
Dow institute of health sciences, psychiatry, Karachi, Pakistan
I.B. Chaudhry
Affiliation:
University of Manchester, brain- behaviour and mental health, Manchester, United Kingdom
N. Husain
Affiliation:
University of Manchester, brain- behaviour and mental health, Manchester, United Kingdom
*
*Corresponding author.

Abstract

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Introduction

There is strong association between depression and mortality rates among patients with CHF. Despite the massive burden of cardiac disease as well as that of depression in Pakistan, there is limited data regarding the prevalence of depression in patients suffering from CHF. The aim of this study was to assess prevalence of depression in patients with CHF and to compare the health related quality of life of depressed and non-depressed patients with CHF.

Methods

A total of 1009 patients diagnosed with CHF were recruited from different public hospitals in Karachi, Pakistan. Depression was assessed at baseline using the Beck Depression Inventory (BDI) and health related quality of life was assessed using Euro Qol (EQ-5D).

Results

Of the 1009 participants recruited to the study, 66.4% (n = 670) met the threshold for depression using the BDI measure. Of the depressed patients, 66.7% (n = 447) were male. Preliminary results indicate that participants who were depressed at baseline had poorer health related quality of life on EQ-5D measures as compared to those who were non-depressed (mean EQ-5D descriptive score 10.45 in depressed patients vs 7.37 in non-depressed patients and mean EQ-5D visual scale score 35.09 in depressed patients vs 52.19 in non-depressed patients).

Conclusion

Considering the high prevalence of depression and its serious negative impact on quality of life of patients suffering from chronic physical illness, it is important to design and test culturally adapted psychosocial interventions to reduce depression and improve quality of life for these patients.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
EV420
Copyright
Copyright © European Psychiatric Association 2016
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