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Depression and cognitive impairment in the elderly: a multicentre study

Published online by Cambridge University Press:  16 April 2020

P Kielholz ,
C Adams ,
P Bech ,
JP Bocksberger ,
A Crombecque ,
G de Girolamo ,
K Fayolle ,
E Holsboer ,
H Katschnig  and
A Korten
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P Kielholz
Affiliation:
Deceased, Arlesheim, Basel, Switzerland
C Adams
Affiliation:
Deceased, Arlesheim, Basel, Switzerland
P Bech
Affiliation:
Department of Psychiatry, Frederiksborg General Hospital, Copenhagen, Denmark
JP Bocksberger
Affiliation:
University Psychogeriatric Clinic, Faculty of Medicine, Geneva, Switzerland
A Crombecque
Affiliation:
University Psychogeriatric Clinic, Faculty of Medicine, Geneva, Switzerland
G de Girolamo
Affiliation:
Division of Mental Health, World Health Organization, Geneva, Switzerland
K Fayolle
Affiliation:
University Psychogeriatric Clinic, Faculty of Medicine, Geneva, Switzerland
E Holsboer
Affiliation:
Psychiatric Polyclinic, University Hospital, Zurich, Switzerland
H Katschnig
Affiliation:
Psychiatric Clinic, Faculty of Medicine, University of Vienna and Ludwig Bolzmann Institute for Social Psychiatry, Vienna, Austria
A Korten
Affiliation:
Social Psychiatry Research Unit, Australian National University, Canberra, Australia
A Küng
Affiliation:
University Psychogeriatric Service, Faculty of Medicine, Lausanne, Switzerland
JW Meyer
Affiliation:
Psychiatric Polyclinic, University Hospital, Zurich, Switzerland
W Pöldinger
Affiliation:
University Psychiatric Clinic, Basel, Switzerland
L Prilipko*
Affiliation:
Psychiatric Clinic, Faculty of Medicine, University of Vienna and Ludwig Bolzmann Institute for Social Psychiatry, Vienna, Austria
I Reubi
Affiliation:
University Psychiatric Clinic, Bern, Switzerland
N Sartorius
Affiliation:
Psychiatric Clinic, Faculty of Medicine, University of Vienna and Ludwig Bolzmann Institute for Social Psychiatry, Vienna, Austria
*
**Correspondence and reprints: Dr L Prilipko, Division of Mental Health, World Health Organization, 1211 Geneva 27, Switzerland.
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Summary

The present study, conducted in collaboration between the Departments of Psychiatry in Swiss Universities and the World Health Organization, had two main goals: to develop assessment methods which could subsequently be used in the Swiss centres in a standard manner; and to make arrangements for continuing collaboration between the centres in Switzerland and the acquisition of new knowledge about the distinctions between depression and cognitive impairment. For this aim, three different groups of elderly patients of either sex were selected during the period of November 1989 to July 1991 for inclusion in the study. The first two groups included the first ten patients of either sex over 60 years of age consecutively contacting the participating institutions and showing depression with or without clinically significant symptoms of cognitive impairment; the control group included patients showing no depression or clinically significant symptoms of cognitive impairment. A total of 125 patients were included in the initial evaluation, 69 of which were reassessed at a seven-month follow up (on average). Each patient was administered a number of clinician-rated or self-report instruments for the assessment of depression, cognitive impairment, disabilities, physical status and onset of disorders. The study has shown that a variety of instruments can be used for the reliable assessment of depression or cognitive impairment in the elderly; but the instruments for the assessment of depression differentiate only poorly between patients with or without cognitive impairment. Because of the importance of identifying both depressed and cognitively impaired patients among the elderly, different assessment instruments targeted at the different symptom clusters need to be administered simultaneously.

Type
Original article
Information
European Psychiatry , Volume 10 , Issue 2 , 1995 , pp. 61 - 74
Copyright
Copyright © Elsevier, Paris 1995

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Footnotes

*

The authors would Iike to dedicate this study to Professor Kielholz's memory. It was he who initiated this study, as well as many other important projects in the field of psychiatry.

References

Banks, PGDickson, ALPlasay, MTThe verbal selective reminding test: preliminary data for healthy elderly. Exp Aging Res 1987; 13: 203–7CrossRefGoogle ScholarPubMed
Been, PGjerris, AAndersen, JRafaelsen, OJWHO Standardized Assessment of Depressive Disorders (WHO/SADD-5) Item combinations and interobserver reliability. Psychopathol 1984; 17: 244–52Google Scholar
Buschke, HSelective reminding for analysis of memory and learning. J Verb Learn Verb Behav 1973; 12: 543–6CrossRefGoogle Scholar
Brunner, CSpiegel, REine Validierungsstudie mit der NOSGER, einem neuen beurteilungsinstrument für die psychogeriatrie. Z Klin Psychol 1990; 19: 211–29Google Scholar
Colsher, PLWallace, RBEpidemiologie considerations in studies of cognitive function in the elderly: methodology and non-dementing acquired dysfunction. Epidemiol Rev 1991; 13: 1–17CrossRefGoogle Scholar
de Bonis, MLebeaux, MODe Boeck, PSimon, MPichot, PMeasuring the severity of depression through a self-report inventory. A comparison of logistic, factorial and implicit models. J Affective Disord 1991; 22: 55–64CrossRefGoogle ScholarPubMed
Delbecque-Derousne, JBeauvois, MFProcesses and aging: a defect of automatic rather than controlled processes?. Arch Gerontol Geriatr 8suppl 1 1989 121–50Google Scholar
Desrosiers, GPrimary or depressive dementia: clinical features. Int J Geriatr Psychiatry 1992; 7: 629–38CrossRefGoogle Scholar
El-Islam, MFMoussa, MAAMalasi, THSuleiman, MAMirza, IAAssessment of depression in Kuwait by principal component analysis. J Affective Disord 1988; 14: 109–14CrossRefGoogle ScholarPubMed
Endicott, JSpitzer, RFleiss, JCohen, JThe Global Assessment Scale: a procedure for measuring overall severity of psychiatric disturbance. Arch Gen Psychiatry 1976; 33: 766–71CrossRefGoogle ScholarPubMed
Folstein, MFFolstein, SEMcHigh, PRMini-Mental State: A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189–98CrossRefGoogle ScholarPubMed
Gupta, RSingh, PVerma, SGarg, DStandardized Assessment of Depressive Disorders: A replicated study from northern India. Acta Psychiatr Scand 1991; 84: 310–2CrossRefGoogle ScholarPubMed
Hamilton, MDevelopment of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967; 6: 278–96CrossRefGoogle ScholarPubMed
Hamilton, MThe Hamilton Rating Scale for Depression.Sartorius, NBan, TA eds. Assessment of Depression. Berlin: Springer Verlag, 1986; 143–52CrossRefGoogle Scholar
Henderson, ASCo-occurrence of affective and cognitive symptoms: The epidemiological evidence. Dementia 1990; 1: 119–23Google Scholar
Henderson, ASJorm, AFMackinnon, AChristensen, HScott, LRKorten, AEPhillips Doyle, CThe prevalence of depressive disorders and the distribution of depressive symptoms in later life: A survey using Draft ICD-10 and DSMIII-R. Psychol Med 1993; 23: 719–29CrossRefGoogle Scholar
Herrmann, MKern, URohmel, JContribution to the search for vigilance-indicative EEG variables. Results of a controlled, double-bind study with pyritinol in elderly patients with symptoms of mental dysfunction. Pharmacopsychiatr 1986; 19: 75–83CrossRefGoogle Scholar
Hofman, ARocca, WABrayne, CBreteler, MMBClarke, MCooper, BCopeland, JRMDartigues, JFDa Silva Droux, AHagnell, OHeeren, TJEngedal, KJonker, CLindesay, JLobo, AMann, AHMolsa, PKMorgan, KO'Connor, DWThe prevalence of dementia in Europe: a collaborative study of 1980–1990 findings. Int J Epidemiol 1991; 20: 736–48CrossRefGoogle ScholarPubMed
Hsiao, JKBartko, JJPotter, WZDiagnosing diagnoses: receiver operating characteristic methods and psychiatry. Arch Gen Psychiatr 1989; 46: 664–7CrossRefGoogle ScholarPubMed
Keegstra, HJDepressive disorders in Ethiopia. A standardized assessment using the SADD schedule. Acta Psychiatr Scand 1986; 73: 658–64CrossRefGoogle Scholar
Kramer, SIReifler, BVDepression, dementia, and reversible dementia. Clin Geriatr Med 1992; 8: 289–97CrossRefGoogle ScholarPubMed
Majodina, MZJohnson, FYAStandardized assessment of depressive disorders (SADD) in Ghana. Br J Psychiatr 1983; 143: 442–6CrossRefGoogle Scholar
Masur, DMFuld, PABlau, ADCrystal, HAronson, MKPredicting development of dementia in the elderly with the selective reminding test. J Clin Exp Neuropsychol 1990; 12: 529–38CrossRefGoogle ScholarPubMed
Masur, DMFuld, PABlau, ADThal, LJLevin, HSAronson, MKDistinguishing normal and demented elderly with the selective reminding test. J Clin Exp Neuropsychol 1989; 11: 615–30CrossRefGoogle ScholarPubMed
Paykel, ESUse of the Hamilton Depression Scale in general practice.Bech, PCoppen, A eds. The Hamilton Scales. Berlin: Springer, 1990; 40–7CrossRefGoogle Scholar
Phillips, CJHenderson, ASThe prevalence of depression among Australian nursing home residents: results using draft ICD-10 and DSM-III-R criteria. Psychol Med 1991; 21: 739–48CrossRefGoogle ScholarPubMed
Pichot, PA self-report inventory on depressive symptomatology and its abridged form (QD2A).Sartorius, NBan, TA eds. Assessment of Depression. Berlin: Springer-Verlag, 1986; 143–52Google Scholar
Reifler, BVLarson, EHanley, RCoexistence of cognitive impairment and depression in geriatric outpatients. Am J Psychiatr 1982; 139: 623–6Google ScholarPubMed
Sartorius, NDavidian, HEmberg, GFenton, FRFuji, IGatspar, MGulbinat, WJablensky, AKielholz, PLehmann, HENaraghi, MShimizu, MShinfuku, NTakahashi, RDepressive Disorders in Different Cultures. Geneva: World Health Organization, 1983Google Scholar
Snow, SSWells, CECase studies in neuropsychiatry: Diagnosis and treatment of coexistent dementia and depression. J Clin Psychiatr 1981; 42: 439–41Google ScholarPubMed
Spiegel, RBrunner, CErmini-Funfschilling, DMonsch, ANotter, MPuxty, JTremmel, LA new behavioral assessment scale for geriatric out-and in-patients: the NOSGER (nurses' observation scale for geriatric patients). J Am Geriatr Soc 1991; 39: 339–47CrossRefGoogle ScholarPubMed
Thienhaus, OJWheeler, BGSimon, SA controlled doubleblind study of high-dose dihydroergotoxine mesylate (Hyderxine (R) ) in mild dementia. J Am Geriatr Soc 1987; 35: 219–23CrossRefGoogle Scholar
Wells, CPseudodementia. Am J Psychiatr 1979; 136: 895–900Google ScholarPubMed
WHO Dose effects of antidepressant medication in different populationsJ Affective Disordsuppl 21986 51–567Google Scholar
WHO The ICD-10 Classification of Mental and Behavioural Disorders. Clinical Descriptions and Diagnostic Guidelines. Geneva: World Health Organization, 1992Google Scholar
WHO Implementation of the Global Strategy for Health for All by the year 2000, second evaluation; and eighth Report on the World Health Organisation,1993Google Scholar
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